DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and syncripl

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_955973.1	Gene:	syncripl / 324384	ZFINID:	ZDB-GENE-030131-3104	Length:	560	Species:	Danio rerio

Alignment Length:	349	Identity:	74/349 - (21%)
Similarity:	124/349 - (35%)	Gaps:	126/349 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 TNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNG- 180
            |.:.|..:|:|:.:.||..||...|||...|:|.|..:|.:.|||||.|.::..:|:|:|:.|.
Zfish   163 TEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLSGLNRGYAFVTFCTKEAAQKAVKLCNNN 227

  Fly   181 -----------ITVRNKRLKVS---------------------------YARPG----------- 196
                       |:|.|.||.|.                           |.:|.
Zfish   228 EIRPGKHIGVCISVANNRLFVGSIPKSKTKDQIVEEFAKVTEGLNDVILYHQPDDKKKNRGFCFL 292

  Fly   197 -------------------------------GESIKDTN---------LYVTNLPRTITDDQLDT 221
                                           .:.|:|.:         |:|.||..|:|::.|:.
Zfish   293 GYEDHKTAAQARRRLMSGKVKVWGNVVTVEWADPIEDPDPEVMAKVKVLFVRNLASTVTEELLEK 357

  Fly   222 IFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAE---- 282
            .|.::|.:.:...|:|        .||:.:.:|:.|.:|::.|:....||  :|:.:..|:
Zfish   358 TFCQFGKLERVKKLKD--------YAFIHFEERDGAVKALAELHGKDLEG--EPIEIVFAKPPDQ 412

  Fly   283 --EHGKAKAAHFMSQMGVVPANVPPP----PPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAI 341
              :..||:.....:||........||    |.:.....|..::..|...:.|...:        .
Zfish   413 KRKERKAQRQAAKTQMYDEYYYYGPPHVHQPTRARGRGARGYSYPHDYYSYEDYYN--------Y 469

  Fly   342 FGLDSENFADLLDGLYRRKYHYPY 365
            :|.|..|        ||..|..||
Zfish   470 YGYDYHN--------YRGGYDDPY 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	33/160 (21%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	20/86 (23%)
syncripl	NP_955973.1	RRM1_hnRNPQ	162..240	CDD:240927	25/76 (33%)
		RRM_SF	242..326	CDD:302621	6/83 (7%)
		RRM3_hnRNPR	338..409	CDD:240938	21/80 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910