DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and hnrnpa0a

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_997810.2	Gene:	hnrnpa0a / 323529	ZFINID:	ZDB-GENE-030131-2249	Length:	305	Species:	Danio rerio

Alignment Length:	177	Identity:	44/177 - (24%)
Similarity:	77/177 - (43%)	Gaps:	32/177 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 NNLCGLSLGSGGSDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYS 157
            |.||.|.:|.                     |....||..|...|...|.:..|.::::.:...|
Zfish     7 NQLCKLFVGG---------------------LNVQTTDDGLRNHFEQYGKLTDCVVVQNQQLKRS 50

  Fly   158 FGYAFVDFTS--EMDSQRAIK--VLNGITVRNKRLKVSYARPGG---ESI-KDTNLYVTNLPRTI 214
            ..:.||.::|  |.||..:.:  :|:|   .|..||.:.||...   |:: |...:::..|...|
Zfish    51 RCFGFVTYSSPDEADSAMSARPHILDG---NNVELKRAVAREDAGKPEALAKVKKIFIGGLKDDI 112

  Fly   215 TDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAI 261
            .:|.|...|.::|::.:..::.||.||:.||..||.:...:.|.:|:
Zfish   113 EEDHLRDCFSQFGAVEKAEVITDKETGKKRGFGFVYFEDNDSADKAV 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	21/83 (25%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	16/59 (27%)
hnrnpa0a	NP_997810.2	RRM1_hnRNPA0	8..86	CDD:240772	23/101 (23%)
		RRM_SF	102..181	CDD:302621	16/58 (28%)
		HnRNPA1	260..286	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920