Protein Alignment Sxl and HNRNPD

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: NP_112738.1
• Gene: HNRNPD / 3184
• HGNCID: 5036
• Length: 355
• Species: Homo sapiens
• Alignment Length: 218
• Identity: 56/218 - (25%)
• Similarity: 87/218 - (39%)
• Gaps: 44/218 - (20%)

  Fly    61 GCGG---SGG-NGGSANNLGGGNMCHLPPMASNNSLNNLCGLSLGSGGSDDLMNDPRASNT---- 117
            |.||   ||| .||||.:.|.      ...||.|..:        .|.|:   :.||.|..
Human    46 GTGGGTASGGTEGGSAESEGA------KIDASKNEED--------EGHSN---SSPRHSEAATAQ 93

  Fly   118 ----NLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKV- 177
                .:.:..|..|.|.::|...|...|.:..|.:..|..||.|.|:.||.|   .:|:...||
Human    94 REEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLF---KESESVDKVM 155

  Fly   178 ------LNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILR 236
                  |||..:..||.|....:   |.:|  .::|..|.....::::...||.:|.:....:..
Human   156 DQKEHKLNGKVIDPKRAKAMKTK---EPVK--KIFVGGLSPDTPEEKIREYFGGFGEVESIELPM 215

  Fly   237 DKLTGRPRGVAFVRYNKREEAQE 259
            |..|.:.||..|:.:.:.|..::
Human   216 DNKTNKRRGFCFITFKEEEPVKK 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	24/94 (26%)
		RRM2_Hu_like	203..281	CDD:240822	11/57 (19%)
HNRNPD	NP_112738.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92		19/62 (31%)
		CBFNT	<60..78	CDD:311868	6/31 (19%)
		RRM1_hnRNPD	99..172	CDD:410150	22/75 (29%)
		RRM2_hnRNPD	183..257	CDD:241027	11/56 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910