Protein Alignment Sxl and Rbm46

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: NP_001129189.1
• Gene: Rbm46 / 310548
• RGDID: 1560205
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 591
• Identity: 123/591 - (20%)
• Similarity: 194/591 - (32%)
• Gaps: 203/591 - (34%)

  Fly    66 GGNGGSANNLGGGNMCHLPPMASNNSLNNL--CGLSLGSGGSDDLMNDPRASNTNLIVNYLPQDM 128
            |.||.|....|..|...|..:......|.:  .|.....|........|......:.|..:|:||
  Rat     8 GTNGCSKVRTGTQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDM 72

  Fly   129 TDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGITVR--------- 184
            .:.||..:|...|.|...|:|.:: :|.:.|||||.:|::.::|.||::||...:|
  Rat    73 YEDELVPVFERAGKIYEFRLMMEF-SGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCV 136

  Fly   185 ---NKRL---------------------------------------------------------- 188
               |.||
  Rat   137 SLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMAR 201

  Fly   189 ---------------KVSYARPGGESIKDTN-----LYVTNLPRTITDDQLDTIFGKY--GSIVQ 231
                           :|.:|.|..|..::|.     |||.||..:.|::.:...|.|:  |::.:
  Rat   202 RKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFNKFKPGAVER 266

  Fly   232 KNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGKAKA--AHFMS 294
            ...|||        .|||.:..||:|..|:|.:|....:|.|  :.|.||:...|...  .|...
  Rat   267 VKKLRD--------YAFVHFFNREDAVAAMSVMNGKCIDGAS--IEVTLAKPVNKENTWRQHLNG 321

  Fly   295 QMG------VVPAN--------VPPPPPQPPAHMAAAFNMMHRDGAME------------KLRSL 333
            |:.      :|.||        :..||..|     ...|..|.....|            ||..:
  Rat   322 QISPNSENLLVYANKEESHSKSLGKPPTLP-----TRLNGQHSPSPPEIERCTYPFFPGTKLTPI 381

  Fly   334 FDAICDAIFGLDSENFADLLDGL--YRRKYHYP----YLXLTPQQQQQLLQHQQQALGFTSSSNN 392
                  :::.|.|.:|...:..|  |..|.::.    ||..|..|..::|...:..:       .
  Rat   382 ------SMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYKIVI-------P 433

  Fly   393 SIGNGNGNDNNMLLYHQQYHQQQ---TQQQRLGNVAAH----NISPNGSNNNINTSNTNNINFNT 450
            :|.||:          |.|....   |..:....:||.    ::..|...::||:.:..:...:|
  Rat   434 AIANGS----------QSYFMPDKLCTTLEDAKELAAQFTLLHLDYNFRRSSINSLSPVSATLST 488

  Fly   451 IRQNGVAALHYLQEQLQLQQPQDQQSQQQQPLTMPSSP--PFQQQSRQSHHNGSSSTLGNQLLAI 513
               ...:.|.|                ..:|.:.||.|  |....:..||       :| |.|.|
  Rat   489 ---GTPSVLPY----------------TSRPYSYPSYPLSPTISLANGSH-------VG-QRLYI 526

  Fly   514 SNNNSF 519
            ||..||
  Rat   527 SNQASF 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	30/164 (18%)
		RRM2_Hu_like	203..281	CDD:240822	25/84 (30%)
Rbm46	NP_001129189.1	RRM1_RBM46	60..137	CDD:240928	24/77 (31%)
		RRM2_RBM46	139..223	CDD:240936	5/83 (6%)
		RRM3_RBM46	235..308	CDD:240940	26/82 (32%)
		DND1_DSRM	392..468	CDD:291380	16/92 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910