DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and elavl3

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	XP_009298008.1	Gene:	elavl3 / 30732	ZFINID:	ZDB-GENE-980526-76	Length:	366	Species:	Danio rerio

Alignment Length:	280	Identity:	101/280 - (36%)
Similarity:	149/280 - (53%)	Gaps:	43/280 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 NGGSANNLGGGNMCHLPPMASNNSLNNLCGLSLGSGGSDDLMNDPRASNTNLIVNYLPQDMTDRE 132
            ||.|..:|..|      |:.|.|            |.:||       |.||||||||||:||..|
Zfish    14 NGPSGTSLPNG------PVISTN------------GATDD-------SKTNLIVNYLPQNMTQEE 53

  Fly   133 LYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGITVRNKRLKVSYARPGG 197
            ..:||.:||.|.:|:::||..||.|.||.||::....|:.:||..|||:.::.|.:|||||||..
Zfish    54 FKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYVDPNDADKAINTLNGLKLQTKTIKVSYARPSS 118

  Fly   198 ESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLT-GRPRGVAFVRYNKREEAQEAI 261
            .||:|.||||:.||:|::...::.:|.:||.|:...||.|::| |..|||.|:|::||.||:|||
Zfish   119 ASIRDANLYVSGLPKTMSQKDMEQLFSQYGRIITSRILVDQVTAGISRGVGFIRFDKRNEAEEAI 183

  Fly   262 SALNNVIPEGGSQPLSVRLAEEHGKAKAAHFMSQMGVVPANVPPPPPQPPAHMAAAFNMMHRDGA 326
            ..||...|.|.::|::|:.|....:......::|:....|.....|..   |....|.:
Zfish   184 KGLNGQKPLGAAEPITVKFANNPSQKTGQALLTQLYQTAARRYTGPLH---HQTQRFRL------ 239

  Fly   327 MEKLRSLFDAICDAIFGLDS 346
                    |.:.:|.:|:.|
Zfish   240 --------DNLLNASYGVKS 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	42/79 (53%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	34/78 (44%)
elavl3	XP_009298008.1	ELAV_HUD_SF	35..365	CDD:273741	91/241 (38%)
		RRM1_Hu	37..114	CDD:241094	38/76 (50%)
		RRM_SF	119..209	CDD:302621	38/89 (43%)
		RRM3_HuC	282..366	CDD:241099
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000313
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910