DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and Pabpc4l

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_001099899.1	Gene:	Pabpc4l / 295010	RGDID:	1559517	Length:	370	Species:	Rattus norvegicus

Alignment Length:	194	Identity:	50/194 - (25%)
Similarity:	92/194 - (47%)	Gaps:	23/194 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 MNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQR 173
            :.:..|..||:.:.....||.|..|.::|...|...:.::|:| .:|.|..:.||.|.|...::.
  Rat   182 LREKPAEFTNVYIKNFGDDMDDESLRSVFSKYGQTLSVKVMKD-ASGKSKRFGFVSFDSHKAAKN 245

  Fly   174 AIKVLNGITV---------------RNKRLKVSYARPGGESIK---DTNLYVTNLPRTITDDQLD 220
            |::.:||..:               |...||..:.:...|.|:   ...||:.||..||.|:.|.
  Rat   246 AVEDMNGRDINGQTIFVGRAQKKVERQAELKEMFEQMKKERIRARQAAKLYIKNLDDTIDDETLR 310

  Fly   221 TIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEH 284
            ..|..:|||.:..::::  .|:.:|...:.:...|.|.:|::.:|..|.  ||:||::.|.::|
  Rat   311 KEFSVFGSICRVKVMQE--AGQSKGFGLICFFSPEAAAKAMAEMNGRIL--GSKPLNIALGQKH 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	22/94 (23%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	23/77 (30%)
Pabpc4l	NP_001099899.1	ELAV_HUD_SF	11..262	CDD:273741	20/80 (25%)
		RRM1_I_PABPs	11..89	CDD:240824
		RRM2_I_PABPs	96..171	CDD:240825
		RRM3_I_PABPs	189..268	CDD:240826	19/79 (24%)
		RRM_SF	293..369	CDD:302621	24/79 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910