DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and Elavl3

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_758827.1	Gene:	Elavl3 / 282824	RGDID:	628892	Length:	367	Species:	Rattus norvegicus

Alignment Length:	229	Identity:	96/229 - (41%)
Similarity:	140/229 - (61%)	Gaps:	24/229 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 GGSANNLGGGNMCHLP--PMASNNSLNNLCGLSLGSGGSDDLMNDPRASNTNLIVNYLPQDMTDR 131
            |...:.:|||     |  |...|..|       ||:.|:.|      .|.||||||||||:||..
  Rat     7 GAMESQVGGG-----PAGPALPNGPL-------LGTNGATD------DSKTNLIVNYLPQNMTQD 53

  Fly   132 ELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGITVRNKRLKVSYARPG 196
            |..:||.:||.|.:|:::||..||.|.||.||:::...|:.:||..|||:.::.|.:|||||||.
  Rat    54 EFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPS 118

  Fly   197 GESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAI 261
            ..||:|.||||:.||:|::..:::.:|.:||.|:...||.|:.||..|||.|:|::||.||:|||
  Rat   119 SASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAI 183

  Fly   262 SALNNVIPEGGSQPLSVRLA----EEHGKAKAAH 291
            ..||...|.|.::|::|:.|    ::.|:|...|
  Rat   184 KGLNGQKPLGAAEPITVKFANNPSQKTGQALLTH 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	42/79 (53%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	34/77 (44%)
Elavl3	NP_758827.1	ELAV_HUD_SF	36..366	CDD:273741	84/182 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000313
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910