DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and Larp7

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_613059.2	Gene:	Larp7 / 28036	MGIID:	107634	Length:	570	Species:	Mus musculus

Alignment Length:	189	Identity:	56/189 - (29%)
Similarity:	77/189 - (40%)	Gaps:	58/189 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 RAIKV-------LNGITVRNKRLKVSYARPGGESIKD---TNLYVTNLPRTITDDQLDTIFGKYG 227
            ||:|.       |.|..:|.|       :|.||..||   ..:||..||:.:|...::.:|||.|
Mouse    86 RALKSSSVVELDLEGTRIRRK-------KPLGERPKDEEERTVYVELLPKNVTHSWIERVFGKCG 143

  Fly   228 SIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQP------------LSVRL 280
            ::|..:|...|.||.|:|.|||.:..:|:|.:||..|||...|...:|            .|:|:
Mouse   144 NVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEAPRKPGIFPKTVKNKPIPSLRV 208

  Fly   281 AEEHGKAK----------------AAHFMSQMGVV-------------PANVPPPPPQP 310
            |||..|.|                :|...|..||.             .|..|..|.||
Mouse   209 AEEKKKKKKKKGRIKKEESVQAKESAVDSSSSGVCKATKRPRTASEGSEAETPEAPKQP 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	8/30 (27%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	30/89 (34%)
Larp7	NP_613059.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		LARP_7	25..105	CDD:153401	5/18 (28%)
		RRM1_LARP7	120..199	CDD:240736	28/78 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	180..364		21/88 (24%)
		RRM_3	442..540	CDD:285930
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000