DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and grld-1

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_741283.1	Gene:	grld-1 / 176827	WormBaseID:	WBGene00017929	Length:	520	Species:	Caenorhabditis elegans

Alignment Length:	219	Identity:	57/219 - (26%)
Similarity:	88/219 - (40%)	Gaps:	41/219 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 NDPRASNTNLIVNYLPQDMTDRELYALFRAIG---------PINTCRIMRDYKTGYSFGYAFVDF 165
            :|..|:.| |.|..:|.|:.:||:..:|...|         ||||           ...||||.|
Worm   163 DDDEATRT-LFVGNMPSDVKEREIRHVFEEHGKVEEVDIKTPINT-----------DAAYAFVMF 215

  Fly   166 --TSEMDSQRAIKVLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGS 228
              ..:....:|.:....|.....|:|:.|    |:|.....|:|..|......:.|...||::|.
Worm   216 QTVDQAIQAKAEEQDRPIRAGGSRMKIGY----GKSQVSRRLFVGGLGSWCDKEILQKAFGEFGF 276

  Fly   229 IVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEE-HGKAKAAHF 292
            :  :||..|.  |:|  .|:|.|.....:|||..:|.......|:.|:.|..|:: ..:.:...|
Worm   277 V--ENIDYDH--GQP--YAYVVYENTHTSQEACRSLRGACISKGNHPIMVDYAKDLTAQPEKQQF 335

  Fly   293 M-------SQMGVVPANVPPPPPQ 309
            |       |.:|......||..|:
Worm   336 MRKRRASKSPVGASAVRTPPGSPK 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	23/90 (26%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	22/77 (29%)
grld-1	NP_741283.1	RRM_SF	33..>93	CDD:302621
		RRM_SF	167..246	CDD:302621	24/94 (26%)
		RRM3_Spen	253..324	CDD:240756	22/76 (29%)
		SPOC	376..482	CDD:285043
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910