Protein Alignment Sxl and tiar-2

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: NP_496718.1
• Gene: tiar-2 / 174909
• WormBaseID: WBGene00012904
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 560
• Identity: 110/560 - (19%)
• Similarity: 184/560 - (32%)
• Gaps: 195/560 - (34%)

  Fly    97 GLSLGSGGSDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYA 161
            |..|.||.     .|||    .|.|..|...:||..|..||..||.:...:|:.:   |.:..||
 Worm    29 GFQLASGS-----EDPR----TLFVANLDPAITDEFLATLFNQIGAVMKAKIIFE---GLNDPYA 81

  Fly   162 FVDFTSEMDSQRAIKVLNGITVRNKRLKVSYA----RPG-----GESIKDTNLYVTNLPRTITDD 217
            ||:|:....:..|::..||..:..|.:.|::|    .||     .|:.:..:::|.:|...|...
 Worm    82 FVEFSDHNQATLALQSHNGRELLEKEMHVTWAFEPREPGENRSKPETSRHFHVFVGDLCSEIDST 146

  Fly   218 QLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAE 282
            :|...|.|:|.:.:..|:||..|.:.:|..||.|.:||:|:.||..:|
 Worm   147 KLREAFVKFGEVSEAKIIRDNNTNKGKGYGFVSYPRREDAERAIDEMN----------------- 194

  Fly   283 EHGKAKAAHFMSQMGVVPANVPPPPPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIFGLDSE 347
                                                      ||.
 Worm   195 ------------------------------------------GAW-------------------- 197

  Fly   348 NFADLLDGLYRRKYHYPYLXLTPQQQQQLLQHQQQALGFTSSSNNSIGNGNGNDNNMLLYHQQYH 412
                    |.||.....:....|.:..:....:....|         |.|.|.|.    ||.|
 Worm   198 --------LGRRTIRTNWATRKPDEDGERGGDRGDRRG---------GGGGGRDR----YHNQ-- 239

  Fly   413 QQQTQQQRLGNVAAHNISPNGSNNNINTSNTNNINFNTIRQ----------------NGVAALHY 461
            .::|..:.....||.|.|       :...|..|:..:.||:                .|.|.:.:
 Worm   240 SEKTYDEIFNQAAADNTS-------VYVGNIANLGEDEIRRAFDRFGPINEVRTFKIQGYAFVKF 297

  Fly   462 LQEQLQLQQPQDQQSQQQQPLTMPSSPPFQQQSRQSHHNGSSSTLGNQLLAIS-----NNNSFNN 521
                      :.::|..:..:.|                 :::.:|.|::..|     ::...:.
 Worm   298 ----------ETKESAARAIVQM-----------------NNADIGGQIVRCSWGKSGDSGKPSE 335

  Fly   522 NSNQSNSFTGNYSNGSAFTSNGAISGSNFPNNPTSSGNFTNNSTNSNPTNSGHFASNLAGSSN-- 584
            ..:.....:|||  |..:.::|...||..|.|    ..|:|.:....|:.:|.......|.:|
 Worm   336 RGSGGGGGSGNY--GYGYGNSGGGGGSGGPGN----SQFSNFNQRPPPSGNGGSGGGSGGQNNQY 394

  Fly   585 -------FTN-HLSGS-NNYTNSNGNFTSNAASSSNFSNN 615
                   :.| ||... |||...:|.....||::|:...|
 Worm   395 WQYYSQYYNNPHLMQQWNNYWQKDGPPPPPAAAASSTGGN 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	25/88 (28%)
		RRM2_Hu_like	203..281	CDD:240822	21/77 (27%)
tiar-2	NP_496718.1	RRM	36..321	CDD:223796	79/432 (18%)
		RRM_SF	42..113	CDD:302621	22/73 (30%)
		RRM_SF	133..207	CDD:302621	26/160 (16%)
		RRM3_TIA1_like	256..326	CDD:240800	12/103 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910