DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sxl and rnp-6

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_491176.1	Gene:	rnp-6 / 171922	WormBaseID:	WBGene00004389	Length:	749	Species:	Caenorhabditis elegans

Alignment Length:	241	Identity:	57/241 - (23%)
Similarity:	94/241 - (39%)	Gaps:	60/241 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 QDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGITVRNKRLKV 190
            :||..|    .|...|||.:..:..|..||:...:|||::.....:..|.:.:||..:..:.|||
Worm   115 EDMLRR----AFDPFGPIKSINMSWDPATGHHKTFAFVEYEVPEAALLAQESMNGQMLGGRNLKV 175

  Fly   191 S--------------YARPGGESI-KDT----NLYVTNLPRTITDDQLDTIFGKYGSIVQKNILR 236
            :              .|:|..:.: ||.    .:||:::...:::..|.::|..:|.||:..:.|
Worm   176 NSMMFQEMRLPQNMPQAQPIIDMVQKDAKKYFRVYVSSVHPDLSETDLKSVFEAFGEIVKCQLAR 240

  Fly   237 DKLTGR-PRGVAFVRYNKREEAQEAISALNNVIPEGGS-----------------QPLSVR---- 279
            .. ||| .||..::.:|......|||:.: |:...||.                 ||.||.
Worm   241 AP-TGRGHRGFGYLEFNNLTSQSEAIAGM-NMFDLGGQYLRVGKCVTPPDALTYLQPASVSAIPA 303

  Fly   280 -------------LAEEHGKAKAAHFMSQMGVVPANVPPPPPQPPA 312
                         :|.|.....:....|:.|...|..|.|..|.||
Worm   304 SVSVACAAITAKVMAAEAAAGSSPKTPSESGGSRAASPAPRAQSPA 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	21/84 (25%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	24/116 (21%)
rnp-6	NP_491176.1	half-pint	5..749	CDD:130706	57/241 (24%)
		RRM1_PUF60	102..177	CDD:240816	19/65 (29%)
		RRM2_PUF60	207..283	CDD:240817	20/77 (26%)
		RRM_SF	657..748	CDD:302621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910