Protein Alignment Sxl and SRSF12

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: NP_542781.3
• Gene: SRSF12 / 135295
• HGNCID: 21220
• Length: 261
• Species: Homo sapiens
• Alignment Length: 417
• Identity: 78/417 - (18%)
• Similarity: 128/417 - (30%)
• Gaps: 170/417 - (40%)

  Fly   192 YARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREE 256
            |.||     .:|:|::.|:......:.|...||:||.||...|..|..|.||||.|:|::....:
Human     4 YTRP-----PNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRD 63

  Fly   257 AQEAISALNNVIPEGGSQPLSVRLAE------EHGKAKAAHFMSQMGVVPANVPPPPPQPPAHMA 315
            |::|:..||.....|  :.:.::.|:      ...|:|..|               |..|..|
Human    64 AEDALYNLNRKWVCG--RQIEIQFAQGDRKTPGQMKSKERH---------------PCSPSDH-- 109

  Fly   316 AAFNMMHRDGAMEKLRSLFDAICDAIFGLDSENFADLLDGLYRRKYHYPYLXLTPQQQQQLLQHQ 380
                                                      ||       ..:|.|::
Human   110 ------------------------------------------RR-------SRSPSQRR------ 119

  Fly   381 QQALGFTSSSNNSIG-NGNGNDNNMLLYHQQ--YHQQQTQQQRLGNVAAHNISPNGSNNNINTSN 442
                  |.|.::|.| |...:|:.....|::  |.|.:::.:.|         |..| .:...|.
Human   120 ------TRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSL---------PRRS-TSARQSR 168

  Fly   443 TNNINFNTIRQNGVAALHYLQEQLQLQQPQDQQSQQQQPLTMPSSPPFQQQSRQSHHNGSSSTLG 507
            |...||.:                                        :.:||.......|.::|
Human   169 TPRRNFGS----------------------------------------RGRSRSKSLQKRSKSIG 193

  Fly   508 NQLLAISNNNSFNNNSNQSNSFTGNYSNGSAFTSNGAISGSNFPNNPTSSGNFTNNSTNSNPTNS 572
                           .:||:|.....|:|:...|:|..|.|...:...|...:||:.|.......
Human   194 ---------------KSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPKGYTNSETKVQTAKH 243

  Fly   573 GHFASNLAGSSNFTNHLSGSNNYTNSN 599
            .||.|:           |.|.:|.:.|
Human   244 SHFRSH-----------SRSRSYRHKN 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	3/4 (75%)
		RRM2_Hu_like	203..281	CDD:240822	24/77 (31%)
SRSF12	NP_542781.3	RRM_SRSF10_SRSF12	10..93	CDD:240758	25/84 (30%)
		PABP-1234	<12..211	CDD:130689	59/343 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..261		51/328 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910