DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and AgaP_AGAP005505

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	XP_315504.4	Gene:	AgaP_AGAP005505 / 1276189	VectorBaseID:	AGAP005505	Length:	511	Species:	Anopheles gambiae

Alignment Length:	220	Identity:	50/220 - (22%)
Similarity:	85/220 - (38%)	Gaps:	60/220 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 QDMTDRELYALFRAIGPINTCRIMRDYKTGYSFG---------------YAFVDFTSEMDSQRAI 175
            :.:|:..|...|...|.|....|::|..||...|               .|::.:....|:.||:
Mosquito    35 KSVTEENLREHFDKFGDIEEIWIVKDRATGEGKGITEQLEKEEQEGARRVAYIKYAKTSDAARAL 99

  Fly   176 KVLNG-----------ITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSI 229
            :.:||           :.|...|.:.|..:...|..|...|:|. :|:.:|::.|...|||||::
Mosquito   100 EEMNGKCVGDNTRPIKVLVAANRQQGSRKQTENEEEKYLRLFVI-IPKDMTEEALREEFGKYGTV 163

  Fly   230 VQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGKAKAAHFMS 294
            ....|:|||:|...:|.|:|::.:...|.:|..         |..|          |.||..
Mosquito   164 DLVTIIRDKVTKEGKGFAYVKFGRFLHAAQAFE---------GCDP----------KYKAVF--- 206

  Fly   295 QMGVVPANVPPPPPQPPAHMAAAFN 319
                       ..|:||.:.:.:.|
Mosquito   207 -----------AEPKPPRNASVSSN 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	19/96 (20%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	22/77 (29%)
AgaP_AGAP005505	XP_315504.4	RRM1_RBM45	24..119	CDD:240812	16/83 (19%)
		RRM_SF	137..210	CDD:302621	25/106 (24%)
		RRM_SF	281..351	CDD:302621
		RRM_SF	422..489	CDD:302621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910