DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and AgaP_AGAP011092

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	XP_309558.3	Gene:	AgaP_AGAP011092 / 1270836	VectorBaseID:	AGAP011092	Length:	634	Species:	Anopheles gambiae

Alignment Length:	426	Identity:	107/426 - (25%)
Similarity:	160/426 - (37%)	Gaps:	114/426 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 TNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIKVLNGI 181
            ||:.|....:|:|:..|..:|...|||.:.|:|.  |.|.|.|:.||.|....|::.|::.|||.
Mosquito   183 TNVYVKNFGEDLTEEALRDMFEKFGPITSHRVMT--KDGKSRGFGFVAFEKPEDAEEAVQKLNGK 245

  Fly   182 TVRN-KRLKVSYARPGGESIKD------------------TNLYVTNLPRTITDDQLDTIFGKYG 227
            .:.: |.|.|..|:...|...:                  .||||.||..||.|::|...|..||
Mosquito   246 ELSDGKVLYVGRAQKKNERQMELKRRFEQLKMERLTRYHGVNLYVKNLDDTIDDERLRKEFAPYG 310

  Fly   228 SIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEHGKAKAAHF 292
            :|....::.|:  ||.:|..||.::..:||.:|::.:|..|.  ||:||.|.||:...:.| :|.
Mosquito   311 TITSAKVMLDE--GRSKGFGFVCFSAPDEATKAVTEMNGRIV--GSKPLYVALAQRKEERK-SHL 370

  Fly   293 MSQMGVVPANVPPPPPQPPAHMAAAFNMMHRDGAMEKLRSLFDAICDAIFGLDSENFADLLDGLY 357
            .||.               .....:..|.|                              :..:|
Mosquito   371 ASQY---------------IQRVNSLRMQH------------------------------IGQVY 390

  Fly   358 RR--KYHYPYLXLTPQQQQQLLQHQQQALGFTS---SSNNSIGNGNGNDN-----------NMLL 406
            ::  .|..|.:.     |.|.....|.|...|:   |:|..:....||.|           .|..
Mosquito   391 QQSGSYFMPTIA-----QPQRFYGPQVAPVRTAPRWSANAQMRPNAGNQNVAANAPAGGYPAMTA 450

  Fly   407 YH---QQYHQQQTQQQRLGNV-AAHNISPNGSNNNINTSNTNNINFNTIRQNGVAALHYLQEQLQ 467
            .|   .||.|       .||| .|:..:||..:...|::...|.......|...|.:.......|
Mosquito   451 AHVANNQYRQ-------AGNVRGANQQAPNAQSAQANSAAMRNAARPITGQQTAANMQTRPVAPQ 508

  Fly   468 LQQPQDQ-------QS----QQQQPLTMPSSPPFQQ 492
            |...|.:       ||    |..||:.:|:.|..||
Mosquito   509 LAAGQARTPNYKFTQSMRNPQVPQPVPIPAQPVAQQ 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	28/80 (35%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	30/77 (39%)
AgaP_AGAP011092	XP_309558.3	PABP-1234	2..624	CDD:130689	107/426 (25%)
		RRM1_I_PABPs	3..82	CDD:240824
		RRM2_I_PABPs	88..164	CDD:240825
		RRM3_I_PABPs	182..261	CDD:240826	28/79 (35%)
		RRM4_I_PABPs	285..362	CDD:240827	32/80 (40%)
		PABP	556..623	CDD:279051
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910