Protein Alignment Sxl and MSI2

DIOPT Version :9

• Sequence 1: NP_001259303.1
• Gene: Sxl / 3772180
• FlyBaseID: FBgn0264270
• Length: 722
• Species: Drosophila melanogaster
• Sequence 2: XP_005257071.1
• Gene: MSI2 / 124540
• HGNCID: 18585
• Length: 346
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 58/249 - (23%)
• Similarity: 94/249 - (37%)
• Gaps: 35/249 - (14%)

  Fly   101 GSGGSDDLMNDPRASNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDF 165
            ||.|:....||.:.....:.:..|....:...|...|...|.|..|.:|||..|..|.|:.||.|
Human     5 GSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTF 69

  Fly   166 TSEMDSQRAIKVL----NGITVRNKRLKVSYARPGGESI--KDTNLYVTNLPRTITDDQLDTIFG 224
            .   |.....|||    :.:..:....||::.|.....:  :...::|..|......:.:...|.
Human    70 A---DPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFE 131

  Fly   225 KYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQEAISAL------NNVIPEGGSQPLSVRLAE- 282
            ::|.:....::.||.|.|.||..||.: :.|:..|.:..:      |.::....:||..|....
Human   132 QFGKVEDAMLMFDKTTNRHRGFGFVTF-ENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPG 195

  Fly   283 EHGKAKAA-----HFMSQMGVV-------------PANVPPPPPQPPAHMAAAF 318
            ..|:|:..     .||..||::             |...|....|.|...|||:
Human   196 TRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPGFPAAAY 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	22/83 (27%)
		RRM2_Hu_like	203..281	CDD:240822	18/83 (22%)
MSI2	XP_005257071.1	RRM1_MSI2	17..109	CDD:410153	22/94 (23%)
		PABP-1234	<35..343	CDD:130689	52/219 (24%)
		RRM2_MSI	111..184	CDD:240769	15/73 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910