DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sxl and hnrnpa3

DIOPT Version :9

Sequence 1:	NP_001259303.1	Gene:	Sxl / 3772180	FlyBaseID:	FBgn0264270	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	XP_031748359.1	Gene:	hnrnpa3 / 100144993	XenbaseID:	XB-GENE-5878765	Length:	385	Species:	Xenopus tropicalis

Alignment Length:	226	Identity:	59/226 - (26%)
Similarity:	96/226 - (42%)	Gaps:	37/226 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SFPSSSSRRGYNDFPGCGGSGGNGGSANNLGGGNMCHLPPMASNNSLNNLCGLSLGSGGSDDLMN 110
            :|.|||||              :.|.|....|...|.:|..|.::...:          :||..:
Frog    44 AFSSSSSR--------------SAGEAAAPFGRERCAMPRGAMDDHWPS----------TDDQGH 84

  Fly   111 DPRASN--TNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFT--SEMD- 170
            :|:...  ..|.:..|..:.||..|...|...|.:..|.:|||.:|..|.|:.||.::  .|:|
Frog    85 EPKEPEQLRKLFIGGLSFETTDDSLREHFEQWGKLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDA 149

  Fly   171 --SQRAIKVLNGITVRNKRL--KVSYARPGGE-SIKDTNLYVTNLPRTITDDQLDTIFGKYGSIV 230
              |.|..|| :|..|..||.  :...||||.. ::|  .::|..:.....:..|...|..||.|.
Frog   150 AMSARPHKV-DGRVVEPKRAVSREDSARPGAHLTVK--KIFVGGIKEDTEEYHLRDYFQSYGKIE 211

  Fly   231 QKNILRDKLTGRPRGVAFVRYNKREEAQEAI 261
            ...::.|:.:|:.||.|||.::..:...:.:
Frog   212 TIEVMEDRQSGKKRGFAFVTFDDHDTVDKIV 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sxl	NP_001259303.1	RRM1_SXL	117..197	CDD:241093	29/86 (34%)
Sxl	NP_001259303.1	RRM2_Hu_like	203..281	CDD:240822	13/59 (22%)
hnrnpa3	XP_031748359.1	RRM1_hnRNPA_like	94..171	CDD:409992	26/77 (34%)
		RRM2_hnRNPA3	184..263	CDD:409996	14/61 (23%)
		HnRNPA1	328..>344	CDD:402981
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920