Protein Alignment Pex6 and AFG2

DIOPT Version :9

• Sequence 1: NP_001027403.2
• Gene: Pex6 / 3772165
• FlyBaseID: FBgn0033564
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_013501.1
• Gene: AFG2 / 851113
• SGDID: S000004389
• Length: 780
• Species: Saccharomyces cerevisiae
• Alignment Length: 820
• Identity: 223/820 - (27%)
• Similarity: 373/820 - (45%)
• Gaps: 196/820 - (23%)

  Fly   118 SPDVNFVNLVIRGRRVRIGK-----PLA------SDEGN-----MTQTVIKQMLQEAPHTIVAQI 166
            |..:..|..:|.|.|:.:.|     |.|      |.:|.     |.:.||:::|.::     ..|
Yeast    99 STTIRSVGNLILGDRLELKKAQVQPPYATKVTVGSLQGYNILECMEEKVIQKLLDDS-----GVI 158

  Fly   167 LPAAQCQPNCLYVQENFYGNILDRFQIRSNCWVQVEHFADEQTIPGIATKAHVYLVADPHELPAE 231
            :|                |.|....:.:          |.:::|..:.|.|....:.|..:|...
Yeast   159 MP----------------GMIFQNLKTK----------AGDESIDVVITDASDDSLPDVSQLDLN 197

  Fly   232 LTEVI--LSN--YFNTPRLMHRGHTYRIEVNAELVGTATYAHYYLIFAHLRHVHLKCIHLETKGS 292
            :.::.  |.|  |.:.|.:..:|.|                          |:
Yeast   198 MDDMYGGLDNLFYLSPPFIFRKGST--------------------------HI------------ 224

  Fly   293 EFELQAIVAKNFSNLVQVPASHSFLPRQVLDSMAIVENYPSGLRKPYKLLRSSVDAFLPKKSACL 357
                      .||...|....:: ||..:  |.|.|    .||.|..:.|:|:::  :|.....|
Yeast   225 ----------TFSKETQANRKYN-LPEPL--SYAAV----GGLDKEIESLKSAIE--IPLHQPTL 270

  Fly   358 -SSKHIFPV--FLLQGERGSGKSKLVSAVAQELGMHIYGADCAEIVSQVPSHTEMKLKAVFAKSQ 419
             ||..:.|.  .||.|..|:||:.|:..||.....|:...:...|||:....||..|:.:|.:::
Yeast   271 FSSFGVSPPRGILLHGPPGTGKTMLLRVVANTSNAHVLTINGPSIVSKYLGETEAALRDIFNEAR 335

  Fly   420 VCEPLMICFHNFEIFGI------DNEGNEDLRLLSAFHVQVQELFNRDRKHPIVVVALTS-DRHL 477
            ..:|.:|...  ||..|      |:.|..:.|:::.....:..:....:   :||:|.|: ...:
Yeast   336 KYQPSIIFID--EIDSIAPNRANDDSGEVESRVVATLLTLMDGMGAAGK---VVVIAATNRPNSV 395

  Fly   478 KPMIQ--GLFLEIINIDMPSKEERFEILRWMHVRETFNDIIYNQKAIEQLPLFSRENQSQFMPRI 540
            .|.::  |.|.:.:.|.:|..:.||:||.....|.:.:..:.:.:||:.
Yeast   396 DPALRRPGRFDQEVEIGIPDVDARFDILTKQFSRMSSDRHVLDSEAIKY---------------- 444

  Fly   541 SPSWRETLNVLQDVAAKSQGFLLGDLQLLYDNAVRMKIRNRLGRTTLDMSHFAKNLT--DMQSSF 603
                         :|:|:.|::..||..|...:|...|:..|| |..::..|:..:|  |::|:.
Yeast   445 -------------IASKTHGYVGADLTALCRESVMKTIQRGLG-TDANIDKFSLKVTLKDVESAM 495

  Fly   604 ADSLGAP------KVPKVYWSDIGGLAKLKDEIQSSIGLPLKHVHLMGKNLRR------SGILLY 656
            .|...:.      ::||||||||||..:||.:::..|.|||:    ..:...|      .|:|||
Yeast   496 VDIRPSAMREIFLEMPKVYWSDIGGQEELKTKMKEMIQLPLE----ASETFARLGISAPKGVLLY 556

  Fly   657 GPPGTGKTLVAKAVATECNLSFLSVQGPELLNMYVGQSEQNVREVFSRARSAAPCVLFLDELDSL 721
            ||||..|||.|||:|||..::||:|:|||:.|.|||:||:.:||:|.:||||||.::|.||:|:|
Yeast   557 GPPGCSKTLTAKALATESGINFLAVKGPEIFNKYVGESERAIREIFRKARSAAPSIIFFDEIDAL 621

  Fly   722 APNRGVAGDSGGVMDRVVSQLLAEMDGMSDGDTSKPIFILAATNRPDLIDPALLRPGRFDKLFYV 786
            :|:|.  |.|....:.|::.||.|:||:.:   .|.:.|:|||||||.||.|||||||.|:..||
Yeast   622 SPDRD--GSSTSAANHVLTSLLNEIDGVEE---LKGVVIVAATNRPDEIDAALLRPGRLDRHIYV 681

  Fly   787 GPCSTAEDKAAVLRAQTQRF-ALDAGVDMEQIAERLKSEMSGADLYSICSNAWLSAVRRTIDGHL 850
            || .....:..:|:..|::| ..::|||:.::|:|.:. .|||::..:|..|.|:|:...:|
Yeast   682 GP-PDVNARLEILKKCTKKFNTEESGVDLHELADRTEG-YSGAEVVLLCQEAGLAAIMEDLD--- 741

  Fly   851 SGTISEKELVPENVIVQEEDFTKSFNKFVPSISAKDLEYF 890
               :::.||         ..|.|:|......|:.:.|.|:
Yeast   742 ---VAKVEL---------RHFEKAFKGIARGITPEMLSYY 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex6	NP_001027403.2	SpoVK	367..847	CDD:223540	165/503 (33%)
		P-loop_NTPase	367..492	CDD:304359	32/133 (24%)
		AAA	653..787	CDD:278434	72/133 (54%)
AFG2	NP_013501.1	CDC48	51..773	CDD:273521	223/820 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910