Protein Alignment Pex6 and SPATA5L1

DIOPT Version :9

• Sequence 1: NP_001027403.2
• Gene: Pex6 / 3772165
• FlyBaseID: FBgn0033564
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_076968.2
• Gene: SPATA5L1 / 79029
• HGNCID: 28762
• Length: 753
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 170/569 - (29%)
• Similarity: 273/569 - (47%)
• Gaps: 95/569 - (16%)

  Fly   367 LLQGERGSGKSKLVSAVAQELGMHIYGADCAEIVSQVPSHTEMKLKAVFAKSQVCE---PLMICF 428
            ||.|..|.||::||.|||:|.|..:.......:....|..||..::.||.:::...   |.::..
Human   238 LLAGPPGVGKTQLVRAVAREAGAELLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFL 302

  Fly   429 HNFEIFGIDNEGNE--DLRLLSAFHVQVQELF---NRDRKHPIVVVALTS-DRHLKPMIQ--GLF 485
            ...:.. ....|:.  :.|:::    ||..|.   :.||:  :|||..|: ...|.|.::  |.|
Human   303 DEMDAL-CPQRGSRAPESRVVA----QVLTLLDGASGDRE--VVVVGATNRPDALDPALRRPGRF 360

  Fly   486 LEIINIDMPSKEERFEILRWMHVRETFNDIIYNQKAIEQLPLFSRENQSQFMPRISPSWRETLNV 550
            ...:.|..|:.::|.|||               |....::|:.|..:               |.:
Human   361 DREVVIGTPTLKQRKEIL---------------QVITSKMPISSHVD---------------LGL 395

  Fly   551 LQDVAAKSQGFLLGDLQLLYDNAVRMKI----RNRLGRTTLDMSHFAKNLTDMQ-SSFADSLGAP 610
            |.::..   |::..||..|...|....:    :|: ....:|...|.:...::| |||...:|..
Human   396 LAEMTV---GYVGADLTALCREAAMHALLHSEKNQ-DNPVIDEIDFLEAFKNIQPSSFRSVIGLM 456

  Fly   611 KVPKVYWSDIGGLAKLKDEIQSSIGLPLK---HVHLMGKNLRRSGILLYGPPGTGKTLVAKAVAT 672
            .:..|.|.:||||..:|.:::.||..|||   ....||.. :..|:|||||||..||.:.:|:||
Human   457 DIKPVDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLT-QPKGVLLYGPPGCAKTTLVRALAT 520

  Fly   673 ECNLSFLSVQGPELLNMYVGQSEQNVREVFSRARSAAPCVLFLDELDSLAPNRGVAGDSGGVMDR 737
            .|:.||:||.|.:|.:.:||.||:.:.::|.:||::.|.:|||||:||:...|..:.....|.:|
Human   521 SCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAILFLDEIDSILGARSASKTGCDVQER 585

  Fly   738 VVSQLLAEMDGMS------DGDTS----------KPIFILAATNRPDLIDPALLRPGRFDKLFYV 786
            |:|.||.|:||:.      .|..|          :.:.|:|||||||::|.|||||||.||:.|:
Human   586 VLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNRSVMIIAATNRPDVLDTALLRPGRLDKIIYI 650

  Fly   787 GPCSTAEDKAAVLRAQTQRFALDAGVDMEQIAERLKSEMSGADLYSICSNAWLSAVRRTIDGHLS 851
            .| ...:.:.::|:..|:...:...|.:|.:|.. ....|||||.::|:.|.|.|::   :..|.
Human   651 PP-PDHKGRLSILKVCTKTMPIGPDVSLENLAAE-TCFFSGADLRNLCTEAALLALQ---ENGLD 710

  Fly   852 GTISEKELVPENVIVQEEDFTKSFNKFVPSISAKDLEYFNNL--KASYS 898
            .|           .|::|.|.||.....||:|.|||..:.||  |..:|
Human   711 AT-----------TVKQEHFLKSLKTVKPSLSCKDLALYENLFKKEGFS 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex6	NP_001027403.2	SpoVK	367..847	CDD:223540	153/514 (30%)
		P-loop_NTPase	367..492	CDD:304359	34/135 (25%)
		AAA	653..787	CDD:278434	65/149 (44%)
SPATA5L1	NP_076968.2	CDC48	22..746	CDD:273521	169/565 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..203
		AAA	237..367	CDD:278434	34/135 (25%)
		AAA	501..651	CDD:278434	65/149 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910