Protein Alignment Pex6 and pex1

DIOPT Version :10

• Sequence 1: NP_001027403.2
• Gene: Pex6 / 3772165
• FlyBaseID: FBgn0033564
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_004915478.1
• Gene: pex1 / 779516
• XenbaseID: XB-GENE-985415
• Length: 1269
• Species: Xenopus tropicalis
• Alignment Length: 819
• Identity: 226/819 - (27%)
• Similarity: 368/819 - (44%)
• Gaps: 152/819 - (18%)

  Fly   111 VYENYAESPDVNFVNLVIRGRRVRIGKPLASDEGNMTQTV-IKQMLQEAPHTIVAQILPAAQCQP 174
            |:..:.:..||  :....|.....:||.....:......: |...::...|..|.::..:...||
 Frog   378 VWHGFDDLKDV--IEYDTRNGNTHVGKVWVPSQLRKKLNINISSAVRIHSHDSVLRLPTSLTLQP 440

  Fly   175 NCLYVQENFYGNILDRFQIRSNCWVQVEHFADEQTIPG------IATKAHV---YLVADPHELPA 230
             ...:..|.:.   |..:...:.|:|.........|.|      |..|..|   :::.|..:|.:
 Frog   441 -AQTLDRNIHE---DEIKAAFSTWLQSNSTLKMPWIAGNTGYIQIILKDEVSDFFIILDKLDLQS 501

  Fly   231 ELTEVILSNYFNTPRLMHRGHTYRIEVNAELVGTATYAHYYLIFAHLRHVH----LKCIHLETKG 291
            ...:.    |...|.:|.:   .:|.||.| ...:..:|        ||:|    |..:.|:..|
 Frog   502 SQDDF----YMLCPSIMEK---TKIHVNFE-PAPSEESH--------RHLHADQNLLYLKLQNLG 550

  Fly   292 SEFELQAIVAKN-FSNLVQVPASHSFLPRQVLDSMAIVENYPSGLRKPYKLLRSSVDAFLPKKSA 355
            ...:|    .|: :.::|     |..|.|.:  |..:|.: .||||....||
 Frog   551 GVSKL----GKSCYDHVV-----HCLLGRPL--SRQLVAS-ASGLRSGGVLL------------- 590

  Fly   356 CLSSKHIFPVFLLQGERGSGKSKLVSAVAQE----LGMHIYGADCAEIVSQVPSHTEMKLKAVFA 416
            |             |.:|||||.|..|:.:|    |..|:...||..:..:...:....|:..|.
 Frog   591 C-------------GPKGSGKSTLAKALCKEASEQLEAHVEEIDCKLLKGKNVENIIQTLEEAFE 642

  Fly   417 KSQVCEPLMICFHNF-EIFGIDN--------EGNEDLRLLSAFHVQVQELFNRDRKHPIVVVALT 472
            ::...:|.:|...:. :|.|:.:        |..:..:|.......::.:.:.|....::... .
 Frog   643 EAAWRQPSVILLDDLDQIAGVASSPELEQSPEATQSKQLAYVLKDLMKNIISMDTLVSLIATC-Q 706

  Fly   473 SDRHLKPMI---QG--LFLEIINIDMPSKEERFEILRWMHVRETFNDIIYNQKAIEQLPLFSREN 532
            |:..|.|::   ||  ||..:..|..|::|.|.|:||.         :|.|:.:.:  ..|.|:.
 Frog   707 SEHSLNPVLISEQGTHLFQCVKPIPPPTQENRSEMLRC---------VIENRLSGD--TAFYRDL 760

  Fly   533 QSQFMPRISPSWRETLNVLQDVAAKSQGFLLGDLQLLYDNAVRMKIRNR-------LGRTTLDMS 590
            ..|::.|                 :::||:..|..:|.:.|:...:..|       |..:|.|..
 Frog   761 DFQYLAR-----------------ETEGFVARDFTMLVERAIESSVSKRQICRIEDLVLSTTDFQ 808

  Fly   591 HFAKNLTDMQSSFADSLGAPKVPKVYWSDIGGLAKLKDEIQSSIGLPLKHVHLMGKNL---RRSG 652
            ...|..|.:....| .|..||  |..|:.:|||..::..::.:|.||.|:..|.. ||   .|||
 Frog   809 RALKGFTPLSLRNA-QLHKPK--KQDWNMVGGLHDIRQVLKDTIELPAKYPELFA-NLPIRHRSG 869

  Fly   653 ILLYGPPGTGKTLVAKAVATECNLSFLSVQGPELLNMYVGQSEQNVREVFSRARSAAPCVLFLDE 717
            :||||.|||||||:|..:|.|..::|:|::|||||:.|:|.|||.||:||:||::|.||:||.||
 Frog   870 VLLYGAPGTGKTLLAGVIAHESRMNFISIKGPELLSKYIGASEQAVRDVFTRAQAAKPCILFFDE 934

  Fly   718 LDSLAPNRGVAGDSGGVMDRVVSQLLAEMDGMSDGDTSKPIFILAATNRPDLIDPALLRPGRFDK 782
            .||:||.||  .|:.||.||||:|:|.::||:   :..:.:::||||:||||||||||||||.|:
 Frog   935 FDSIAPRRG--HDNTGVTDRVVNQMLTQLDGV---EGLQGVYVLAATSRPDLIDPALLRPGRLDE 994

  Fly   783 LFYVGPCSTAEDKAAVLRAQTQRFALDAGVDMEQIAERLKSEMSGADLYSICSNAWLSAVRRTID 847
            ..|..| ...:.:..:|:..:....||..||::.||. |....:||||.::..||.|.|:..
 Frog   995 CLYCPP-PDQDSRFEILKGLSHSMLLDENVDLKHIAS-LTDYFTGADLKALLYNAQLEAIHT--- 1054

  Fly   848 GHLSGTISEKELVPENVIVQEEDFTKSFNKFVPSISAKD 886
             :||.|:.:     :|....:.|.:.|...|:...||.|
 Frog  1055 -NLSVTVPQ-----DNNSGSDSDMSLSSIIFLNHSSASD 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex6	NP_001027403.2	SpoVK	<367..600	CDD:440232	53/257 (21%)
		RPT1	<609..883	CDD:440835	117/276 (42%)
pex1	XP_004915478.1	PEX-2N	11..93	CDD:462730
		PEX-1N	99..174	CDD:462729
		CDC48	<587..1052	CDD:273521	167/530 (32%)