Protein Alignment Pex6 and Pex1

DIOPT Version :10

• Sequence 1: NP_001027403.2
• Gene: Pex6 / 3772165
• FlyBaseID: FBgn0033564
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_652016.1
• Gene: Pex1 / 45460
• FlyBaseID: FBgn0013563
• Length: 1006
• Species: Drosophila melanogaster
• Alignment Length: 919
• Identity: 217/919 - (23%)
• Similarity: 385/919 - (41%)
• Gaps: 237/919 - (25%)

  Fly    82 LTPIPNRLYDLLIKN-----------EQIKSEHLVFASQE--------VYENYAESPDVNFVNLV 127
            |||:.:......:||           |::|.:....:|:.        ::...|:..|| |||
  Fly   206 LTPLTHSSTVSNVKNTIQRNKRQDHMERLKKDLRRESSRSFEFRVIRGLWREQAQESDV-FVN-- 267

  Fly   128 IRGRRVRIGKPL--------------ASDEGN--MTQTVIKQMLQEAPHTIVAQILPAAQCQPN- 175
                    ||.|              |:|:..  ..:||...:..:.|.|    |.|:.:...|
  Fly   268 --------GKHLPEFFDLDLFYCMHTAADKDYYVRVRTVEDDIEDDLPET----IHPSIELNANL 320

  Fly   176 --CLYVQENFYGNILDRFQIRSNCWV-----QVEHFADEQTIPGIATKAHVYLVADPHELPAELT 233
              .|.::|      |:|..:|....|     ::|.||:::|        |..::.:..:
  Fly   321 MKLLGIKE------LERVVLRPKTTVVNFVEKIELFANKKT--------HYKIMENAFK------ 365

  Fly   234 EVILSNYFNTPRLMHRGHTYRIEVNAELVGTATYAHYYLIFAHLRHVHLKCIHL-ETKGSEFELQ 297
            ..::....:.|.|.::....|:|  .:|:.|..     ::..|.|:..:....| |:|....:|.
  Fly   366 RFVIERTQHKPMLFNQEEVVRLE--DDLLVTVG-----ILPEHFRYCVVDAQFLKESKIYAADLV 423

  Fly   298 AIVAK------------NFSNLVQVPASHSFLPRQVLDSMAIVENYPSGLRKPYKLLRSSVDAFL 350
            ..|.:            :..:|:|:| .:..:..||:..:
  Fly   424 RPVGEIIKEETPPTSPLSVQDLIQLP-EYDKIVDQVVQEL------------------------- 462

  Fly   351 PKKSACLSSKHIFPVF-----LLQGERGSGKSKLVSAVAQEL-------------GMHIYGADCA 397
             :.:.|||:.:  .|.     ||.|..|:||:.||..:..:|             |....|....
  Fly   463 -RMNLCLSADN--SVMRQCNVLLAGASGTGKTVLVERILDQLSRKPDYCHFEFFHGSRSKGRKTE 524

  Fly   398 EIVSQVPSHTEMKLKAVFAKSQVCEPLMICFHNFEIF--GIDNEGNEDLRLLSAFHVQVQELFNR 460
            .|        :..|:.:|.......|.::...|.::.  ....:.::|           .|.:||
  Fly   525 SI--------QKDLRNIFTSCLQHAPAIVVLENLDVLAHAAGEQSSQD-----------GEYYNR 570

  Fly   461 --DRKHPIVVVALTSDRHLKPMIQGLFLEIINIDMPSKEERFEILRWMHVRETFNDIIYNQKAIE 523
              |..:.::|...|::..       ..:..:| ::.:..:|....|..||.:|          :.
  Fly   571 MADTVYQLIVQYTTNNAI-------AVIATVN-ELQTLNKRLSSPRGRHVFQT----------VA 617

  Fly   524 QLPLFSRENQSQFMPRISPSWRETLNVLQDV-----AAKSQGFLLGDLQLLYDNAVRMKIRNRLG 583
            :||...|.::...:..:.    ..:||.:|:     :..::|:...||....:.|:....|....
  Fly   618 RLPNLERADREIILRELC----SHINVAKDLDLVKFSNLTEGYRKCDLVQFVERAIFYAYRISKT 678

  Fly   584 RTTLDMSHFAKNLTDMQS---------------SFADSLGAPKVPKVYWSDIGGLAKLKDEIQSS 633
            :..|......::|....|               :.|:.:...::|        ||..:...::..
  Fly   679 QPLLTNDQLIESLEHTNSYCLQGIQSNQRTGNDADANEMRVEELP--------GLESVVGVLEEV 735

  Fly   634 IGLPLKHVHLMGKN-LR-RSGILLYGPPGTGKTLVAKAVATECNLSFLSVQGPELLNMYVGQSEQ 696
            :..|.::..:...: || ::|:|||||||||||.:...:||..||..:||:|||||..|:||||:
  Fly   736 LMWPSRYPTIFNASPLRNQAGVLLYGPPGTGKTYLVSQLATSWNLRIISVKGPELLAKYIGQSEE 800

  Fly   697 NVREVFSRARSAAPCVLFLDELDSLAPNRGVAGDSGGVMDRVVSQLLAEMDGMSDGDTSKPIFIL 761
            |||.:|:|||||.|||||.||.|||||.||  .||.||.||||:|||.|:||:   :..:.:.::
  Fly   801 NVRNLFNRARSARPCVLFFDEFDSLAPKRG--HDSTGVTDRVVNQLLTELDGV---EGLQGVTVI 860

  Fly   762 AATNRPDLIDPALLRPGRFDKLFYVGPCSTAEDKAAVLRAQTQRFALDAGVDMEQIAERLKSEMS 826
            |||:||:|:||||||.||.|:|... |...|..:..:..|.:...:||..||.:..|.: .:..:
  Fly   861 AATSRPELLDPALLRSGRIDRLVEC-PLPDAPARVRIFEALSSTLSLDECVDFDWFAGK-TANYT 923

  Fly   827 GADLYSICSNAWLSAVRRTID--GHLSGTISEKELVPENVIVQEEDFTKSFNKFVPSISAKDLEY 889
            |||:.||.::|.::||:..:.  ||        |.:.:.:.::::...:||....||:||.|:..
  Fly   924 GADIQSILTSANMAAVKEALAQFGH--------EKLAKKISLKQKHLIESFQTTRPSLSASDVAK 980

  Fly   890 FNNLKASYS 898
            ::...|.::
  Fly   981 YHRTYARFT 989

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex6	NP_001027403.2	SpoVK	<367..600	CDD:440232	42/254 (17%)
		RPT1	<609..883	CDD:440835	110/277 (40%)
Pex1	NP_652016.1	PEX-1N	93..168	CDD:462729
		CDC48	365..983	CDD:273521	179/723 (25%)
		RecA-like_PEX1_r2	728..885	CDD:410934	84/161 (52%)