Protein Alignment Pex6 and Nvl

DIOPT Version :10

• Sequence 1: NP_001027403.2
• Gene: Pex6 / 3772165
• FlyBaseID: FBgn0033564
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_001099450.1
• Gene: Nvl / 289323
• RGDID: 1311270
• Length: 855
• Species: Rattus norvegicus
• Alignment Length: 571
• Identity: 201/571 - (35%)
• Similarity: 307/571 - (53%)
• Gaps: 56/571 - (9%)

  Fly   367 LLQGERGSGKSKLVSAVAQELGMHIYGADCAEIVSQVPSHTEMKLKAVFAKSQVCEPLMICFHNF 431
            ||.|..|.||:.|..|:|.||.:.|......||||.|...:|.||:.:|.::....|.::.....
  Rat   301 LLHGPPGCGKTLLAHAIAGELDLPILKVAAPEIVSGVSGESEQKLRDLFDQAVSNAPCIVFIDEI 365

  Fly   432 EIFGIDNE-GNEDL--RLLSAFHVQVQELFNRDRKHPIVVVALTS-DRHLKPMIQ--GLFLEIIN 490
            :......| .::|:  |:::.....:.:|.|......::||..|: ...|.|.::  |.|...:.
  Rat   366 DAITPKREVASKDMERRIVAQLLTCMDDLNNVAATARVLVVGATNRPDSLDPALRRAGRFDREVC 430

  Fly   491 IDMPSKEERFEIL----RWMHVRETFN--------------DIIYNQK-----AIEQLPLFSREN 532
            :.:|.:..|..||    |.:.:.||||              |::...:     |:.:: |..|:.
  Rat   431 LGIPDEASRERILQTLCRKLRLPETFNFSHLAHLTPGFVGADLMALCREAAVCAVHRV-LMRRQE 494

  Fly   533 QSQFMPRIS--PSWRETLNVL-QDVAAKSQGFLLGDLQLLYDNAVRMKIRNRLGRTTLDMSHFAK 594
            |.:..|...  ||..|....| .:..:::|..|...|.||.|.....:  .::....|:::.|..
  Rat   495 QQRTEPETGGLPSDGEQGRSLGAEPPSETQDELQRLLGLLRDQDPISE--EQMQGLCLELNDFIV 557

  Fly   595 NLTDMQSSFADSLGAPKVPKVYWSDIGGLAKLKDEIQSSIGLPLKH---VHLMGKNLRRSGILLY 656
            .|:::|.| |...|...||.|.|:|:|.|..:::|:..:|..|:::   ...:|. :..:|:||.
  Rat   558 ALSEVQPS-AKREGFVTVPNVTWADVGALEDIREELTMAILAPVRNPEQFRALGL-VAPAGVLLA 620

  Fly   657 GPPGTGKTLVAKAVATECNLSFLSVQGPELLNMYVGQSEQNVREVFSRARSAAPCVLFLDELDSL 721
            ||||.||||:|||||.|..|:|:||:||||||||||:||:.||:||.||:::||||:|.||:|:|
  Rat   621 GPPGCGKTLLAKAVANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDAL 685

  Fly   722 APNRGVAGDSGGVMDRVVSQLLAEMDGMSDGDTSKPIFILAATNRPDLIDPALLRPGRFDKLFYV 786
            .|.|  :....|...|||:|||.||||:   :|.:.:||||||||||:||||:|||||.||..:|
  Rat   686 CPRR--SDRETGASVRVVNQLLTEMDGL---ETRQQVFILAATNRPDIIDPAILRPGRLDKTLFV 745

  Fly   787 GPCSTAEDKAAVLRAQTQ---RFALDAGVDMEQIAERLKSE-MSGADLYSICSNAWLSAVRRTID 847
            |....| |:.|:|:..|:   :..||..||:|.||...:.: .:||||.::...|.|.|:|:.|.
  Rat   746 GLPPPA-DRVAILKTITKNGTKPPLDEDVDLEAIANDHRCDCYTGADLSALVREASLCALRQEIT 809

  Fly   848 GHLSGTISEKELVPENVIVQEEDFTKSFNKFVPSISAKDLEYFNNLKASYS 898
            |..:| |...||.     |..:.|.::|.|..||||.||...:..|:.|.|
  Rat   810 GQKNG-IGTAELT-----VSHKHFEEAFRKVKPSISVKDQRMYEALQRSLS 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex6	NP_001027403.2	SpoVK	<367..600	CDD:440232	62/264 (23%)
		RPT1	<609..883	CDD:440835	128/280 (46%)
Nvl	NP_001099450.1	Nucleolin_bd	2..71	CDD:465247
		CDC48	<255..855	CDD:273521	201/571 (35%)