Protein Alignment Pex6 and prx-6

DIOPT Version :10

• Sequence 1: NP_001027403.2
• Gene: Pex6 / 3772165
• FlyBaseID: FBgn0033564
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_504268.1
• Gene: prx-6 / 266912
• WormBaseID: WBGene00004195
• Length: 720
• Species: Caenorhabditis elegans
• Alignment Length: 814
• Identity: 231/814 - (28%)
• Similarity: 379/814 - (46%)
• Gaps: 153/814 - (18%)

  Fly    93 LIKNEQIKSEHLVFASQEVYENYAESPDVNFVNLVIRGRRVRIGKPLASDEGNMTQTVIKQMLQE 157
            |:.||:::.:.:|..|.......:..|...:...::..:.|:....:.:|.|. :..:.:.|..:
 Worm    27 LLWNEEVELKIVVDQSGASINTLSIHPVTCWSLGILDSQLVKTSFTITTDHGK-SSNIERVMKVQ 90

  Fly   158 APHTIVAQILPAAQCQPNCLY----VQENFYGNILDRFQIRSNCWVQVEHFADEQTIPGIATKAH 218
            ...::....|..::|....|:    |:.....||...|:..            |..|| |:..|.
 Worm    91 TSTSVKIGSLRISRCDVFNLFGPDLVKNVAVDNITPNFKFH------------ETPIP-ISEDAK 142

  Fly   219 VYLVADP----------HELPAEL--------TEVILSNYFN--TPRLMHRGHTYRIEVNAELVG 263
            :.|:..|          |.|...|        .:||....:|  |.:..|.  .|:::|::.
 Worm   143 LSLMRQPSVAKNIRLEKHHLKQILKSANVFYKNDVIRITNYNAYTDKTTHL--FYKLDVSSS--- 202

  Fly   264 TATYAHYYLIFAHLRHVHLKCIHLETKGSEFELQAIVAKNFSNLVQVPASHSFLPRQVLDSMAIV 328
                               .|| :::..:.:|..|:..       .:|.|:..|...:..||
 Worm   203 -------------------PCI-MDSSTAVYETSAVSQ-------SLPFSNFLLKNSLTSSM--- 237

  Fly   329 ENYPSGLRKPYKLLRSSVDAFLPKKSA--CLSSKHIFPVFLLQGERGSGKSKLVSAVAQELGMHI 391
                          |::|.......||  .:|.|.:  |.|:.|..||||..:....|.|...:.
 Worm   238 --------------RTTVFRMTQIYSAQKTISKKAL--VLLVTGASGSGKRLMSRVFASETHRNF 286

  Fly   392 YGADCAEIVSQVPSHTEMKLKAVFAKSQVCEPLMICFHNFEIFGIDNEGNEDLRLLSAFHVQVQE 456
            :..|..|:|.:..|.:|.|..:.:.|:::.:..::...|..:..||.....|.|:|.    .:::
 Worm   287 FEVDGYEMVCENASTSEAKWTSWWEKAKLLQNCVLFIRNSNVLAIDQFNALDRRILQ----YMEQ 347

  Fly   457 LFNRDRKHPIVVVALTSDRHLKPM-IQGLFLEIINIDMPSKEERFEILRWMHVRETFNDIIYNQK 520
            ..:...|..::....|......|. ::.|.|...:.:...:.:          |:|:.....|:|
 Worm   348 KLSEPSKITVIFSCNTDTMSSMPANVKNLALYTFSAEFMDEND----------RKTWLQYYLNEK 402

  Fly   521 AIEQLPLFSRENQSQFMPRISPSWRETLNVLQDVAAKSQGFLLGDLQLLYDNAVRMKIRNRLGRT 585
                                         :...||.|:.||.|.:|:.|..|..::||..:..:.
 Worm   403 -----------------------------LANHVAKKTSGFTLAELEKLVKNGKKVKIEEKEEKV 438

  Fly   586 TLDMSHFAKNLTDMQSSFADSLGAPKVPKVYWSDIGGLAKLKDEIQSSIGLPLKHVHLMG-KNLR 649
            ..|:      :....|:|||::||||:|.|.|.|:|||.:.|..:..||     ..:|.| :.|:
 Worm   439 YEDL------IDKRNSNFADAIGAPKIPNVRWEDVGGLEETKQTVLESI-----RTNLFGSRALK 492

  Fly   650 RSGILLYGPPGTGKTLVAKAVATECNLSFLSVQGPELLNMYVGQSEQNVREVFSRARSAAPCVLF 714
            ||||:|||.||.||||:|||||||..::||||:||||||.||||||:|:|:||.||:.|:|||:|
 Worm   493 RSGIILYGSPGCGKTLIAKAVATEFKIAFLSVKGPELLNKYVGQSEENLRKVFERAKQASPCVIF 557

  Fly   715 LDELDSLAPNRGVAGDSGGVMDRVVSQLLAEMDGMSDGDTSKPIFILAATNRPDLIDPALLRPGR 779
            .||:||||||||..||||||:||:|||||||:|.:.:...:| :|::.|||||||:|.:|:.|||
 Worm   558 FDEIDSLAPNRGRNGDSGGVIDRIVSQLLAELDKLHNSPLTK-VFVMGATNRPDLLDNSLMTPGR 621

  Fly   780 FDKLFYVGPCSTAEDKAAVLRAQTQRFALDAGVDMEQIAERLKSEMSGADLYSICSNAWLSAVRR 844
            ||||..|.|....|.|..:|.|.:::...:..||:.:||.::..:||||.|:||.|||.::|:..
 Worm   622 FDKLVEVKPGEDVESKTKILEAVSRKMRFEEDVDLREIASKVDEKMSGAQLFSIISNAGMAAIVE 686

  Fly   845 TIDGHLSGTISEKELVPENVIVQEEDFTKSFNKF 878
            ||.     :|.:.:...:::.|.:....:|..:|
 Worm   687 TIQ-----SIEDGKTENQSIRVAQRHLLESVKRF 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex6	NP_001027403.2	SpoVK	<367..600	CDD:440232	42/233 (18%)
		RPT1	<609..883	CDD:440835	134/271 (49%)
prx-6	NP_504268.1	AAA	261..363	CDD:459627	22/105 (21%)
		RPT1	451..715	CDD:440835	136/274 (50%)