Protein Alignment Pex6 and pex6

DIOPT Version :10

• Sequence 1: NP_001027403.2
• Gene: Pex6 / 3772165
• FlyBaseID: FBgn0033564
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_593468.1
• Gene: pex6 / 2542437
• PomBaseID: SPAC17A5.01
• Length: 948
• Species: Schizosaccharomyces pombe
• Alignment Length: 1007
• Identity: 288/1007 - (28%)
• Similarity: 460/1007 - (45%)
• Gaps: 239/1007 - (23%)

  Fly    54 KWPWFLY-------PGYLTYAVYWRYAKYYKGKFLLT--PIPNRLYDLLIKNEQIKSEHLVFASQ 109
            |..|..|       ||:..::.|         .::.|  .|..|:: |.|.||.::...:..:..
pombe    19 KQAWVSYLWLKKALPGFEEHSAY---------VYMTTNPTIAGRIF-LPINNEDLEDGTVEISGY 73

  Fly   110 E------VYENYAESPDVNFVNLV---------------IRGRR--------------VRIGKP- 138
            :      :|.:......::||.|:               |:||.              |::.:|
pombe    74 DNLLADALYISTIAPVKLDFVQLIVIDDNSQDQDAIIERIKGRNAILMESDFINQNILVQVCQPV 138

  Fly   139 ---------------------LASDEGNM-------TQTVIKQMLQEAPHTIVAQILPAAQCQPN 175
                                 |||:|.|:       |:|..:.:::  |..:..:|   ..|..|
pombe   139 RHGVVDSETKFVIERKDSFTFLASNEKNISSFKRGKTETDAELVIR--PSKVHTEI---QWCLQN 198

  Fly   176 CLYVQENFYGNILDRFQIRSNCWVQVEHFADEQTIPGIAT----KAH--VYLVADPHELPAELTE 234
            |..:...|  .:|.....::.|.:.: ..:|.:.:.|||:    ..|  |.|....|... |..|
pombe   199 CSLIHVPF--ELLFNVGKKNGCPISL-RLSDGKNVYGIASIKSDTEHDSVQLSPSLHYFD-EFNE 259

  Fly   235 VILSNYFNTPRLMHRGHTYRI--EVNAELVGTATYAHYYLIFA-------------HLRHVHLKC 284
            .::|.......|:.||.:..|  .::...:.|.:.....|:.|             .|:...:.|
pombe   260 SVISEEGTEAFLVARGPSVGIASRISLRTIPTQSCFSEKLLKAANLCVVQQVKQKVFLQSKQIFC 324

  Fly   285 IHLE--------------TKGSE----FELQAIVAKNFSNLVQVPASHSFLPRQVLDSMAIVENY 331
            :.:.              |:.::    :.::.|...|..|:.......|.    |||:.......
pombe   325 VPINSLMANSDSVDILELTRNTDAYIWYSVEEIDPLNTYNIYYTNEDTSI----VLDTQLSHRLL 385

  Fly   332 PSGLRKP-----------YKLLRSSVDAFLPKKSACLSSKHIFPVFLLQGERGSGKSKLVSAVAQ 385
            || ||||           .||||.....|.|::....:     |.|||.|...:||:|.|..||.
pombe   386 PS-LRKPLLNFVKVHPPSQKLLRFCRAFFDPQQVPGFN-----PFFLLHGNPFTGKTKAVEEVAS 444

  Fly   386 ELGMHIYGADCAEIVSQVPSHTEMKLKAVFAKSQVCEPLMICFHNFEIFGIDNEGNEDLRLLSAF 450
            .....::.....|.......|.|.||. :|.::.|..|..|.|            .:||.:||
pombe   445 LFSAPVFTISSYEFADATADHLEAKLD-MFVQNVVKSPCAIIF------------VKDLDVLS-- 494

  Fly   451 HVQVQELFNRDRKHPIVVVALTSDR-HLKPMIQGLFLEIINIDM-PSKEERFEILRWMH------ 507
                                ::||. ::.|..:.:.:.:..||: .|.:.|:.::...|
pombe   495 --------------------ISSDEGNIVPGSKSIQILLSKIDLVKSPQGRYIVIGTCHSIEKIP 539

  Fly   508 ---VRETFNDIIYNQ----KAIEQLPLFSRENQSQFMPRISPSWRETLNVLQDVAAKSQGFLLGD 565
               :.|:|.::.:::    :.:|.|.:::  |......|||         |:|||.|:.....|:
pombe   540 YEILSESFFELKFSELEMDERLELLKIYA--NNVIIDKRIS---------LKDVALKTNSMSFGE 593

  Fly   566 LQLLYDNAVRMKIRNRLGRTTLDMSHFAKN---LTDMQSSFA-DSLGAPK------VPKVYWSDI 620
            |:.|.|:..:..: :|:.||..|......:   :|:.....: :.:...|      ||||.|.||
pombe   594 LECLPDHMTKAAV-DRIKRTGYDNDSIILSGPIITEQDVDVSINRIRKEKSNTIFTVPKVNWDDI 657

  Fly   621 GGLAKLKDEIQSSIGLPLKHVHLMGKNLR-RSGILLYGPPGTGKTLVAKAVATECNLSFLSVQGP 684
            |||.:.|..::.::.|||:...|..:.|: |||:||||||||||||:|||||||.:|.|:|::||
pombe   658 GGLEEAKTVLRDTLQLPLQFPELFSQGLKPRSGVLLYGPPGTGKTLLAKAVATELSLEFVSIKGP 722

  Fly   685 ELLNMYVGQSEQNVREVFSRARSAAPCVLFLDELDSLAPNRGVAGDSGGVMDRVVSQLLAEMDGM 749
            ||||||||:||.|||.||.:||:::|||:|.|||||:||:||.:.|||.||||||||||||:|.:
pombe   723 ELLNMYVGESEANVRNVFEKARNSSPCVIFFDELDSIAPHRGNSSDSGNVMDRVVSQLLAELDSI 787

  Fly   750 SDGDTSKPIFILAATNRPDLIDPALLRPGRFDKLFYVGPCSTAEDKAAVLRAQTQRFALDAGVDM 814
            |. |.:|.:|::.|||||||:||:||||||||||.|:|...:.|.||::|||.|:.|.||..:|:
pombe   788 SK-DNNKYVFVIGATNRPDLLDPSLLRPGRFDKLVYLGINKSEESKASMLRALTKTFKLDETIDL 851

  Fly   815 EQIAERLKSEMSGADLYSICSNAWLSAVRRTIDG-----HLSGT-ISEKELVPEN-------VIV 866
            .:||:......:|||:|::||:|.|||::|..:.     ..||| :|.:|....|       :.:
pombe   852 NEIAKNCHPNFTGADMYALCSDAVLSAIKRKTNEIDLLIQASGTDLSTEEFFKRNENQDSLELRI 916

  Fly   867 QEEDFTKSFNKFVPSISAKDLEYFNNLKASYS 898
            .:|||..|..|..||||.::|..:..::..:|
pombe   917 TKEDFLTSLKKLRPSISEQELHRYEMVRHQFS 948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex6	NP_001027403.2	SpoVK	<367..600	CDD:440232	53/250 (21%)
		RPT1	<609..883	CDD:440835	152/293 (52%)
pex6	NP_593468.1	CDC48	<426..941	CDD:273521	208/562 (37%)