Protein Alignment Pex6 and Pex6

DIOPT Version :10

• Sequence 1: NP_001027403.2
• Gene: Pex6 / 3772165
• FlyBaseID: FBgn0033564
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_663463.1
• Gene: Pex6 / 224824
• MGIID: 2385054
• Length: 981
• Species: Mus musculus
• Alignment Length: 818
• Identity: 270/818 - (33%)
• Similarity: 415/818 - (50%)
• Gaps: 157/818 - (19%)

  Fly   136 GKPLASDEGNMTQTVIKQMLQEAPHTIVAQILPAAQCQP---NCLYVQENFYGNILDRFQIRSNC 197
            |:|||..            |...|.|:...:    .|.|   ..|.:|....|:|..  :.:.:|
Mouse   264 GEPLADG------------LVFLPATLAFNL----GCDPLEVGELRIQRYLEGSIAP--ENKGSC 310

  Fly   198 WVQVEHFADEQTIPG--IATKAHVYLVADPHELPAELTEVILSNYFNTPRLMHRGHTYRIEVNAE 260
                      ..:||  .|.:.|:.:::.||.......:.:|..:|.|||::..|         :
Mouse   311 ----------SPLPGPPFARELHIEILSSPHYSANGNYDHVLYRHFQTPRVVQEG---------D 356

  Fly   261 LVGTATYAHYYLIFAHL------RHVHLKCIHLETKGSEFELQAIVAKNFSNLVQVPASHSFLPR 319
            ::..:|.....::...|      |.:..|                |.|......:.||| :||..
Mouse   357 VLCVSTAGQVEILEGSLERLPRWREMFFK----------------VKKTVGEAPEGPAS-AFLAD 404

  Fly   320 QVLDSMAI-------VENYPSGLRKPY-KLLRSSVDAFLPKKSACLSSKHIFP---------VFL 367
            ....|:.:       |.:.|||...|: .|....::|.:.:..|.| ..|:.|         ..|
Mouse   405 TTHTSLYLAGTALSHVPSLPSGRSPPWDSLSPPGLEALVNELCAIL-KPHLQPGGTLLTGTSCVL 468

  Fly   368 LQGERGSGKSKLVSAVAQELGMHIYGADCAEIVSQVPSHTEMKLKAVFAKSQVCEPLMICFHNFE 432
            |||..||||:..|:|....||:|:....|:.:.:......|.||:|.|::::.|.|.::.....:
Mouse   469 LQGPPGSGKTTAVTAACSRLGLHLLKVPCSSLCADSSRAVETKLQATFSRARRCRPAVLLLTAVD 533

  Fly   433 IFGIDNEG-NEDLRLLSAF-HVQVQELFNRD---RKHPIVVVALTSD-RHLKPMIQGLFLEIINI 491
            :.|.|.:| .||.|:.:.. |:    |.:.|   |..|::|||.||. :.|...:|..|...:.:
Mouse   534 LLGRDRDGLGEDARVAATLRHL----LLDEDALSRCPPLMVVATTSRVQDLPTDVQTAFPHELEV 594

  Fly   492 DMPSKEERFEILRWMHVRETFNDIIYNQKAIEQLPLFSRENQSQFMPRISPSWRETLNVLQDVAA 556
            .:.|:.:|..||               |.....|||....|                  |..:|.
Mouse   595 PVLSEAQRLSIL---------------QALTAHLPLGQEVN------------------LPQLAR 626

  Fly   557 KSQGFLLGDLQLLYDNAVRMK-IRNRLGRTTLDMSH-----------------FAKNLTDMQSSF 603
            :..||::|||..|..:..|.. .|.|...:...:|.                 |.:.|..:|::.
Mouse   627 RCAGFVVGDLYALLTHTCRAACTRIRASGSAGGLSEEDEGDLCVAGFPLLAEDFGQALDQLQTAH 691

  Fly   604 ADSLGAPKVPKVYWSDIGGLAKLKDEIQSSIGLPLKHVHLMGKNLRRSGILLYGPPGTGKTLVAK 668
            :.::|||::|.|.|.|:|||..:|.||..:|.|||:|..|:...|||||:||:|||||||||:||
Mouse   692 SQAVGAPRIPSVSWHDVGGLQDVKKEILETIQLPLEHPELLSLGLRRSGLLLHGPPGTGKTLLAK 756

  Fly   669 AVATECNLSFLSVQGPELLNMYVGQSEQNVREVFSRARSAAPCVLFLDELDSLAPNRGVAGDSGG 733
            ||||||:|:||||:||||:||||||||:||||||:|||:||||::|.||||||||:||.:|||||
Mouse   757 AVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGG 821

  Fly   734 VMDRVVSQLLAEMDGMSDGDTSKPIFILAATNRPDLIDPALLRPGRFDKLFYVGPCSTAEDKAA- 797
            ||||||||||||:||:   .:::.:|::.|||||||:|||||||||||||.:||   .:||:|:
Mouse   822 VMDRVVSQLLAELDGL---HSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVG---ASEDRASQ 880

  Fly   798 --VLRAQTQRFALDAGVDMEQIAERLKSEMSGADLYSICSNAWLSAVRRTIDGHLSGTISEKELV 860
              ||.|.|::|.|:|.|.:..:.:....:::||||||:||:|.::|::|.:.....|.    ||.
Mouse   881 LRVLSAITRKFKLEASVSLANVLDCCPPQLTGADLYSLCSDAMMTALKRRVRDLEEGL----ELR 941

  Fly   861 PENVIVQEEDFTKSFNKFVPSISAKDLEYFNNLKASYS 898
            ...:::..||..::..:..||:|.::|..:..::..::
Mouse   942 SSALLLTMEDLLQAAARLQPSVSEQELLRYKRIQRKFA 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex6	NP_001027403.2	SpoVK	<367..600	CDD:440232	63/256 (25%)
		RPT1	<609..883	CDD:440835	154/276 (56%)
Pex6	NP_663463.1	CDC48	<467..978	CDD:273521	218/547 (40%)