Protein Alignment Pex6 and mac-1

DIOPT Version :10

• Sequence 1: NP_001027403.2
• Gene: Pex6 / 3772165
• FlyBaseID: FBgn0033564
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_496814.1
• Gene: mac-1 / 174974
• WormBaseID: WBGene00003119
• Length: 813
• Species: Caenorhabditis elegans
• Alignment Length: 675
• Identity: 189/675 - (28%)
• Similarity: 303/675 - (44%)
• Gaps: 150/675 - (22%)

  Fly   313 SHSFLPRQVLDSMAIVENYPSGLRKPYKLLRSSVDAFLPKKSACLSSKHIFPV--FLLQGERGSG 375
            |.:..||   :|....|:.....|:..::.|.::....||..|.|.   :.|.  |::.|..|.|
 Worm   193 SDTISPR---ESHVKFEHIGGADRQFLEVCRLAMHLKRPKTFATLG---VDPPRGFIVHGPPGCG 251

  Fly   376 KSKLVSAVAQELGMHIYGADCAEIVSQVPSHTEMKLKAVFAKSQVCEPLMICFHNFEIFGIDNEG 440
            |:....|||.||.:.:......|:||.|...||.|::.:|..::...|.::...:.:......|.
 Worm   252 KTMFAQAVAGELAIPMLQLAATELVSGVSGETEEKIRRLFDTAKQNSPCILILDDIDAIAPRRET 316

  Fly   441 NE---DLRLLSAFHVQVQELFNRDRKHP--------------------------IVVVALTS--- 473
            .:   :.|::|.....:.||....|:.|                          ::|:..||
 Worm   317 AQREMERRVVSQLCSSLDELVLPPREKPLKDQLTFGDDGSVAIIGDSPTAAGAGVLVIGTTSRPD 381

  Fly   474 --DRHLKPMIQGLFLEIINIDMPSKEERFEILRWMHVRETFNDIIYNQKAIEQLPLFSRENQSQF 536
              |..|:.  .|.|...|::.:|.:..|.:||..:.......|:
 Worm   382 AVDGGLRR--AGRFENEISLGIPDETAREKILEKICKVNLAGDV--------------------- 423

  Fly   537 MPRISPSWRETLNVLQDVAAKSQGFLLGDLQLLYDNAVRMKIRNRLGRTTLDMSHFAKNLT---- 597
                         .|:.:|..:.|::..|||.|...|.::.| :|:..|.:..:...||||
 Worm   424 -------------TLKQIAKLTPGYVGADLQALIREAAKVAI-DRVFDTIVVKNEGHKNLTVEQI 474

  Fly   598 -------------------------DMQSSFAD-------------SLGAPKVPKVYWSDIGGLA 624
                                     .:|.||.|             ..|...||.|.|.|||.|.
 Worm   475 KEELDRVLAWLQGDDDPSALSELNGGLQISFEDFERALSTIQPAAKREGFATVPDVSWDDIGALV 539

  Fly   625 KLKDEIQSSIGLPLKHVH---LMGKNLRRSGILLYGPPGTGKTLVAKAVATECNLSFLSVQGPEL 686
            :::.:::.||..|:|...   .:|.:.|..||||.||||.||||:|||||.|..::|:||:||||
 Worm   540 EVRKQLEWSILYPIKRADDFAALGIDCRPQGILLCGPPGCGKTLLAKAVANETGMNFISVKGPEL 604

  Fly   687 LNMYVGQSEQNVREVFSRARSAAPCVLFLDELDSLAPNRGVAGDSGGVMDRVVSQLLAEMDGMSD 751
            ||||||:||:.||.||.|||.:.|||:|.||:|:|.|.|.....|||.  |:|:|||.||||:
 Worm   605 LNMYVGESERAVRTVFQRARDSQPCVIFFDEIDALVPKRSHGESSGGA--RLVNQLLTEMDGV-- 665

  Fly   752 GDTSKPIFILAATNRPDLIDPALLRPGRFDKLFYVGPCSTAEDKAAVLRAQTQ---RFALDAGVD 813
             :..:.:|::.||||||::|.|:|||||.||:.:| ...:.||:..:||..|:   |..|...:|
 Worm   666 -EGRQKVFLIGATNRPDIVDAAILRPGRLDKILFV-DFPSVEDRVDILRKSTKNGTRPMLGEDID 728

  Fly   814 MEQIAERLK-SEMSGADLYSICSNAWLSAVRRTI---DGHLSGTISEKELVPENVIVQEEDFTKS 874
            ..:||:..: :..:||||.::...:.|.|::..:   |..:.|             |....|.::
 Worm   729 FHEIAQLPELAGFTGADLAALIHESSLLALQARVLENDESVKG-------------VGMRHFREA 780

  Fly   875 FNKFVPSISAKDLEYFNNLKASYSV 899
            .::..||::..|.:.:.::|..|.:
 Worm   781 ASRIRPSVTEADRKKYEHMKKIYGL 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex6	NP_001027403.2	SpoVK	<367..600	CDD:440232	53/295 (18%)
		RPT1	<609..883	CDD:440835	115/283 (41%)
mac-1	NP_496814.1	Nucleolin_bd	5..65	CDD:465247
		CDC48	<191..804	CDD:273521	188/672 (28%)