Protein Alignment Pex6 and Pex1

DIOPT Version :10

• Sequence 1: NP_001027403.2
• Gene: Pex6 / 3772165
• FlyBaseID: FBgn0033564
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_061513544.1
• Gene: Pex1 / 1271027
• VectorBaseID: AGAMI1_013104
• Length: 1141
• Species: Anopheles gambiae
• Alignment Length: 885
• Identity: 213/885 - (24%)
• Similarity: 371/885 - (41%)
• Gaps: 230/885 - (25%)

  Fly    80 FLLTPIPNRLY--DLLIKNEQIKSEHLVFASQEVYENYAESPDVNFVNLVIRGRRVRIGKPLASD 142
            ||||...||.|  ::.:..:..:.....:.:.|:.:...|..::|      .|.:|.: ||:.:
Mosquito   404 FLLTTNDNREYYVNVRLAGDGERFPRNAYPTVEINDRLMEQLEIN------HGEKVTL-KPIRN- 460

  Fly   143 EGNMTQTVIKQMLQEAPHTIVAQILPAAQCQPNCLYVQENFYGNILDRFQ--IRSNCWVQVEHFA 205
                ...::.::          ::|||.:..|   .::|    :|:::|:  :..|
Mosquito   461 ----ALNIVDRI----------ELLPATKVAP---IIEE----DIVEKFKQFVLHN--------- 495

  Fly   206 DEQTIPGIATKAHVYLVADPH--ELPAELTEVILSNYFNTPRLMHRGHTYRIEVNAELVGTATYA 268
                     :|.|..|:....  :||         .|:.|.:|......|.: :|:.:
Mosquito   496 ---------SKIHALLLNQEQLFKLP---------EYYLTLKLQPPALKYCL-INSTI------- 534

  Fly   269 HYYLIFAHLRHVHLKCIHLETKGSEFELQAIVAKNFSNLVQVPASHSFL------PRQVLDSMAI 327
                    |||..:.|                    :..|:..|.:|.:      |..:.|:.::
Mosquito   535 --------LRHSKICC--------------------TGEVKPVAGYSDVEGTKKKPAALKDAESV 571

  Fly   328 VENYPSGLRKPYKLLRSSVDAFLPKKSACLSSKHIFPV---FLLQGERGSGKSKLVSAVAQ---E 386
            .|.....:.|..:::....|..  |.:.||.::...|.   ..:.|...||:..:...:.:   |
Mosquito   572 EECKLVKIEKIERIVEECTDRL--KYALCLDARCKVPQQCNMFIAGSSQSGRKTVCDNILKRLAE 634

  Fly   387 LGMHIYGA--DCAEIVSQVPSHTEMKLKAVFAKSQVCEPLMIC-FHNFEIF---GID-------N 438
            :..:.:..  |||:...:.|...:..|:         ..|.:| ||:..:.   |:|       :
Mosquito   635 VPFYCFSTTFDCAKHKGRKPDSIQKDLR---------HTLYLCMFHSPAVLFMDGLDVLAHQPGD 690

  Fly   439 EGNEDLRLLSAFHVQVQELFNRD-----RKHPIVVVA-LTSDRHLKPMIQG-----LFLEIINID 492
            :...|    :.:|.:|.::..:.     ..:||.|:| ::|..:|...:..     ||.:.:.:.
Mosquito   691 QNTPD----AEYHNKVSDMIRKQIEEFTGNNPIAVIASISSSSNLNRRLHSSRGYHLFQQHVKLP 751

  Fly   493 MPSKEERFEILRWMHVRETFNDIIYNQKAIEQLPLFSRENQSQFMPRISPSWRETLNVLQDVAAK 557
            ...|.:|...|:.:.|                      :.|.:...||  .|:...|       :
Mosquito   752 NLDKADREAALKSLFV----------------------QRQCKLDRRI--DWKRLAN-------Q 785

  Fly   558 SQGFLLGDLQLLYDNAV--------------------RMKIRNRLGRTTLDMSHFAKNLTDMQSS 602
            ::|:.:|.|..|.|.||                    .:.:.||.  ..:.:.:..:..||....
Mosquito   786 TEGYAIGSLVQLVDRAVFYAYKQDGKFPFVTEAMVSEALDVTNRY--CLVGIENHKQQATDELEE 848

  Fly   603 FADSLGAPKVPKVYWSDIGGLAKLKDEIQSSIGLPLKHVHLM-GKNLR-RSGILLYGPPGTGKTL 665
            ..|.:...|||        ||....:..|..:..|.:...:. ...|| ::||||:||||||||.
Mosquito   849 EDDEVPGDKVP--------GLEGAIEVFQEVLMWPTRFPKIFEASPLRNQAGILLFGPPGTGKTY 905

  Fly   666 VAKAVATECNLSFLSVQGPELLNMYVGQSEQNVREVFSRARSAAPCVLFLDELDSLAPNRGVAGD 730
            :...:|...||..:||:|||||..|:||||:|||.:|.|||||.|||||.||.|||||.||  .|
Mosquito   906 LVSKLAKTWNLRMISVKGPELLAKYIGQSEENVRNLFDRARSAKPCVLFFDEFDSLAPRRG--HD 968

  Fly   731 SGGVMDRVVSQLLAEMDGMSDGDTSKPIFILAATNRPDLIDPALLRPGRFDKLFYVG-PCSTAED 794
            |.||.||||:|||.|:||:   :..:.:.::.||:||:|:||||||.||.|:|.... |..||
Mosquito   969 STGVTDRVVNQLLTELDGV---EGLQGVTVIGATSRPELLDPALLRSGRIDRLVECTLPGVTA-- 1028

  Fly   795 KAAVLRAQTQRFALDAGVDMEQIAERLKSE-MSGADLYSICSNAWLSAVRRTIDGHLSGTISEKE 858
            :..:....::...||..||:.:.|  :||| .:|||:.||.:.|.:.||:..:.       ::.|
Mosquito  1029 RLEIFSNHSKSLTLDKDVDLREFA--VKSEYYTGADIRSILTTANMLAVQECLS-------NDPE 1084

  Fly   859 LVPENVIVQEEDFTKSFNKFVPSISAKDLEYFNNLKASYS 898
            .|||.:.|.:....::|:...||:|.:|:..:....|.::
Mosquito  1085 KVPEQITVSQRHLAEAFSSTRPSLSPRDIAKYRETYARFT 1124

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex6	NP_001027403.2	SpoVK	<367..600	CDD:440232	46/279 (16%)
		RPT1	<609..883	CDD:440835	115/277 (42%)
Pex1	XP_061513544.1	None