DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33934 and slc13a2

DIOPT Version :9

Sequence 1:	NP_001163660.1	Gene:	CG33934 / 3772159	FlyBaseID:	FBgn0064119	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_001008098.1	Gene:	slc13a2 / 493460	XenbaseID:	XB-GENE-480294	Length:	624	Species:	Xenopus tropicalis

Alignment Length:	614	Identity:	211/614 - (34%)
Similarity:	306/614 - (49%)	Gaps:	101/614 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 MIPLITLPIMIYGVLENNLAFQCMYLVANMALFWITEAIPLYLTALFPVVFLPLFGILTSEKVCS 93
            ::||..||:.:  |:....| .|.:::..|||||.|||:||.:||||||:..|:.||:.|..|||
Frog    19 LVPLFLLPLPL--VVPTKEA-SCGFVIIVMALFWCTEALPLAVTALFPVLLFPMMGIMDSTAVCS 80

  Fly    94 FYFSDTVVMFIGGLLIALAIEYSNLHQRIALNTILIVGCSPRRLHFGLVMVTCFISLWISNSAAT 158
            .|..||.::||||||:|:::|..|||:||||..:||||..|..|..|.::||.|:|:||||:|.|
Frog    81 QYLKDTNMLFIGGLLVAISVEKWNLHKRIALRVLLIVGVKPALLLLGFMVVTAFLSMWISNTATT 145

  Fly   159 AMMCPIVKAVLNEMETQN-------------------------------IFAI---YKTQEE--E 187
            |||.||.:|||.::.|..                               |.|:   |.|..|  |
Frog   146 AMMIPIAQAVLQQLHTSEERVDKPSEETKKNVNGMDNSMYESVLPNGKMILAVENTYATVNEGFE 210

  Fly   188 PVEEGDPPHPS--------------------------------TISMAFYFGIAYSSSIGGCGTL 220
            ..:....|.||                                .|.......:.||:||||..||
Frog   211 MQDSTKDPEPSKLEKESIGPIVIELEDEKQKEEKQKLRLEKHLKICKGMTLSVCYSASIGGIATL 275

  Fly   221 IGTGTNLTYKGLYDTRFPNSDEKIDFPIFMAYSVPFVVLVLIFLTYFSLQVTHMGL-FRPNSKIG 284
            .||..||..||..|..||.::..|:|..:..::.| .:.||:.|::..||...:|. |:.|...|
Frog   276 TGTTPNLVMKGQMDELFPENNNVINFASWFGFAFP-TMFVLLALSWLWLQFMFLGFNFKKNFGCG 339

  Fly   285 QEVKKGAESQDVVKDVIKQRKAELGPMSCHEIQVGLLFVLMIFLLFTRKPGFFPGWADFL----N 345
            ...::..:.:...| :|.....:||.|:..||.|.:||:|::.|.|||:|||.||||...    .
Frog   340 GNSEQKEKEKRAFK-IISGEHKKLGAMTFAEISVLVLFILLVLLWFTREPGFMPGWATISFNKDG 403

  Fly   346 AKAIGSGPPVFFATILLFALPTQYTFFKY-------CCGKAPFPGQTLDACLSWVYCQKYTPFGL 403
            .:.:.......|.::::|..|::...|||       ..|..| ..:...|.|.|....:..|:.:
Frog   404 KEMVTDATVAIFVSLMMFFFPSELPSFKYREDTDTEKPGMKP-KFRVPPALLDWKTVNEKMPWNI 467

  Fly   404 AFLLGGGFALAEGSRVSGMAKMLGESLAFAGEMHSV----LVISMCIIISLF--CTAFASNVAIC 462
            ..|||||||||:||..||::..|||.|.   .:.|:    :.:.:|::::.|  ||   ||||..
Frog   468 VILLGGGFALAKGSEESGLSLWLGEKLT---PLQSIPPAAIALILCLLVATFTECT---SNVATT 526

  Fly   463 NILIPIFSEMALAIEVHPMKLTFPAALACSLAFHLPVSTPPNAIISGFTGLKTKYMAIAGILPTC 527
            .:.:||.:.||.||.::|:.:..|..|:.||||.|||:||||||...:..||...||.||:|...
Frog   527 TLFLPILASMAKAIHLNPLYIMLPCTLSASLAFMLPVATPPNAIAFSYGQLKVIDMAKAGLLLNI 591

  Fly   528 WAFLCLLFTGTVWTMLIYP-GTTEFPSWA 555
            ...|.:......|...::. ||  |||||
Frog   592 LGVLTITLAINSWGFYMFDLGT--FPSWA 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33934	NP_001163660.1	dass	45..540	CDD:273267	198/580 (34%)
CG33934	NP_001163660.1	ArsB_NhaD_permease	52..524	CDD:304373	194/557 (35%)
slc13a2	NP_001008098.1	ArsB_NhaD_permease	34..609	CDD:389757	199/584 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000