DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33934 and CG7309

DIOPT Version :9

Sequence 1:	NP_001163660.1	Gene:	CG33934 / 3772159	FlyBaseID:	FBgn0064119	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_609468.4	Gene:	CG7309 / 34509	FlyBaseID:	FBgn0032314	Length:	528	Species:	Drosophila melanogaster

Alignment Length:	537	Identity:	137/537 - (25%)
Similarity:	241/537 - (44%)	Gaps:	42/537 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 CGFHWRGKATAMIPLITLPIMIYGVLENNLAFQCMYLVANMALFWITEAIPLYLTALFPVVFLPL 82
            |.:|::|.....||::..||:|...:   |..:.:||...:.|.:|...:.....|...:||:|:
  Fly    24 CKYHYKGVLLLFIPILLAPILIGTPV---LICRFIYLTLCLYLIYILNLMARGAAAFIYMVFIPV 85

  Fly    83 FGILTSEKVCSFYFSDTVVMFIGGLLIALAIEYSNLHQRIALNTILIVGCSPRRLHFGLVMVTCF 147
            .||.:|:::...|::|.:......:.:.:.::.|.|..|:|...|.:||.|.:.|...|.:....
  Fly    86 AGIASSKEISVSYYTDLIFFVYSAIFMGIMMDSSKLSDRLAFIVISLVGGSLKFLQIFLTIAAAI 150

  Fly   148 ISLWISNSAATAMMCPIVKAVLNEMETQNIFAIYKTQEEEPVEEGDPPHPSTISMAFYFGIAYSS 212
            :|:.::.:.:.|....:.:||:.|.:...:..:  ..||:|.|.|..|:|:...:..|....|::
  Fly   151 VSILVNPTISAAFWMKVSQAVMVEYDNGGLIKL--NSEEKPYEIGSKPYPTRPVIGIYLTCCYAA 213

  Fly   213 SIGGCGTLIGTGTNLTYKGLYDTRFPNSDEKIDFPIFMAYSVPFVVLVLIFLTYFSLQVTHMGLF 277
            |:....:.|     :...|:....|..|...::..:.||......::|:||.    |||..:||
  Fly   214 SLAASLSPI-----VNPNGVISDGFGGSLTVLEIGMLMAGPALMGLVVMIFW----LQVLFLGL- 268

  Fly   278 RPNSKIGQEVKK------GAESQDVVKDVIKQRKAELGPMSCHEIQVGLLFVLMIFLLFTRKPGF 336
                 :|..||:      ||::.  .|....:||..|||...:.|....|.:||..|:.||||..
  Fly   269 -----LGGSVKRDLAEMAGAKAG--FKQTASERKQALGPWGIYPILALSLILLMFLLVATRKPRI 326

  Fly   337 FPGWADFLNAKAIGSGPPV--FFATILLFALPTQYTFFKYCCGKAPFPGQTLDACLSWVYCQKYT 399
            |.|| |.:|.|| .||..|  ...:||.||:|..|.|.:|...:.|......::.|.|......|
  Fly   327 FTGW-DSINYKA-ESGLSVAGIGMSILFFAIPANYIFCRYYVCRQPEKEGPANSLLGWKAVNNNT 389

  Fly   400 PFGLAFLLGGGFALAEGSRVSGMAKMLGESLAFAGEMHSVLVISMCIIISLFCTAFASNVAICNI 464
            |:...|:||..|:.:..|.|.|:...|.:|:....:..::.......::....|..:....:..:
  Fly   390 PWAEIFMLGAAFSFSYSSAVCGLNTYLADSMNSDNKGFNMKSFICGALLGTLWTTLSPATTVAKL 454

  Fly   465 LIPIFSEMALAIEVHPMKLTFPAALACSLAFHLPVSTPPNAIISGFTGLKTKYMAIAGILPTCWA 529
            .:|   .|..|    ....:.|.|.|....|.||||:|.|.|::|:..::.....:.|.:.|.:.
  Fly   455 ALP---TMVTA----GNSFSLPFATALHNQFLLPVSSPANTIVAGWGNVRPFQFLLGGSILTLFM 512

  Fly   530 FLCLL--FTGTVWTMLI 544
            | |.:  ||....||::
  Fly   513 F-CTIAGFTILFRTMVL 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33934	NP_001163660.1	dass	45..540	CDD:273267	127/504 (25%)
CG33934	NP_001163660.1	ArsB_NhaD_permease	52..524	CDD:304373	121/479 (25%)
CG7309	NP_609468.4	CitT	31..523	CDD:223547	132/523 (25%)
CG7309	NP_609468.4	ArsB_NhaD_permease	76..523	CDD:304373	122/475 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448683
Domainoid	1	1.000	122	1.000	Domainoid score	I1235
eggNOG	1	0.900	-	-		E1_COG0471
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	85	1.000	Inparanoid score	I1587
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000298
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890