DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33934 and SPBC3B8.04c

DIOPT Version :9

Sequence 1:	NP_001163660.1	Gene:	CG33934 / 3772159	FlyBaseID:	FBgn0064119	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_596410.1	Gene:	SPBC3B8.04c / 2540279	PomBaseID:	SPBC3B8.04c	Length:	867	Species:	Schizosaccharomyces pombe

Alignment Length:	566	Identity:	127/566 - (22%)
Similarity:	231/566 - (40%)	Gaps:	145/566 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VKRCCGFHWRGKATAMIPLITLPIMI--YGVLENNLAFQCMYLVANMALFWITEAIPLYLTAL-- 74
            :.||   .:......:|.:|.:.|::  :.|::|.....|:.|:..::|.|.||||||::|:.
pombe   398 IPRC---FFNSTIATLITIIVIFILLLSFPVIDNREQNNCLALLVMVSLLWATEAIPLFVTSFLV 459

  Fly    75 -FPVVFL---------PLFGILTSEKVCSFYFSDTVVMFIGGLLIALAIEYSNLHQRIALNTILI 129
             |..|||         ||.|..:::.:.|..::.|:|:.:||..||.|:...::.:|:|.:.:..
pombe   460 PFMTVFLKILRDENGSPLSGKESTKVIFSSMWNPTIVLLLGGFTIAAALSKYHIAKRLATSILAH 524

  Fly   130 VGCSPRRLHFGLVMVTCFISLWISNSAATAMMCPIVKAVLNEMETQNIFAIYKTQEEEPVEEGDP 194
            .|..||.:....:.|..|.|:||||.||..:...|::.:|..:..::.||
pombe   525 AGRKPRSVLLTNMFVAMFASMWISNVAAPVLCFSIIQPLLRNLPAESDFA--------------- 574

  Fly   195 PHPSTISMAFYFGIAYSSSIGGCGTLIGTGTNLTYKGLYDTRFPNSDEKIDFPIFMAYSVPFVVL 259
                   .....|||.:|::||..:.|.:..|:       ....|.|....:..:.|.|:| |.|
pombe   575 -------KILIVGIALASNVGGIASPISSPQNI-------VALQNMDPAAGWGEWFAVSIP-VSL 624

  Fly   260 VLIFLTYFSLQVTHMGLFRPNSKIGQEVKKGAES-------------QDVVKDVIKQRKAEL-GP 310
            :.||..:|.|.   .||.:.......:::...::             ..:|...:::|..|: |.
pombe   625 LCIFSIWFLLS---FGLLKDEHITLAKIRSTKDTFTGVQWFISIVTIGTIVLWCLERRFDEVFGD 686

  Fly   311 MSCHEIQVGLLFVLMIF--LLFTRKPGFFPGWADFLNAKAIGSGPPVFFATILLFALPTQYTFFK 373
            |..    :.|:.:::.|  .|.|::        ||.|          |..|:::.|:
pombe   687 MGV----IALVPIIVFFGTGLLTKE--------DFNN----------FLWTVIVLAM-------- 721

  Fly   374 YCCGKAPFPGQTLDACLSWVYCQKYTPFGLAFLLGGGFALAEGSRVSGMAKM----LGESLAFAG 434
                                               ||.||.:....||:.::    :|.:::...
pombe   722 -----------------------------------GGVALGKVVSSSGLLELIALKIGNAVSSLN 751

  Fly   435 EMHSVLVISMCIIISLFCTAFASNVAICNILIPIFSEMALAI-EVHPMKLTFPAALACSLAFHLP 498
            ....:|:.|   .::|..::|.|::....:::||..|:...: :.||......:.:.||||..||
pombe   752 TFRVLLIFS---ALTLVVSSFISHIVAAMVVLPIVHEVGSRLADPHPRLFVLASGMMCSLAMALP 813

  Fly   499 VSTPPN--AII----SGFTGLKTKYMAIAGILPTCWAFLCLLFTGT 538
            .|..||  ||:    :|...||......|||..|..:|:.||..||
pombe   814 TSGFPNMTAIMMENEAGKRYLKVSDFLKAGIPATLISFVILLLIGT 859

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33934	NP_001163660.1	dass	45..540	CDD:273267	121/533 (23%)
CG33934	NP_001163660.1	ArsB_NhaD_permease	52..524	CDD:304373	112/510 (22%)
SPBC3B8.04c	NP_596410.1	COG5408	1..301	CDD:227695
		SPX_PHO87_PHO90_like	2..282	CDD:269899
		CitT	409..861	CDD:223547	125/552 (23%)
		SLC13_permease	435..858	CDD:238535	117/523 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	130	1.000	Domainoid score	I1327
eggNOG	1	0.900	-	-		E1_COG0471
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I1393
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000298
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860