DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33934 and nac-2

DIOPT Version :9

Sequence 1:	NP_001163660.1	Gene:	CG33934 / 3772159	FlyBaseID:	FBgn0064119	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_001254976.1	Gene:	nac-2 / 187898	WormBaseID:	WBGene00003518	Length:	585	Species:	Caenorhabditis elegans

Alignment Length:	545	Identity:	160/545 - (29%)
Similarity:	269/545 - (49%)	Gaps:	63/545 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PLITLPIMIYGVLENNLAFQCMYLVANMALFWITEAIPLYLTALFPVVFLPLFGILTSEKVCSFY 95
            ||:.:|::.:|.     .::|::.:..::.:||.||.|:.:|:|||:...|:..|:.|:::...|
Worm    53 PLVAVPLLFFGP-----EYRCLFSIIFLSTYWIGEAFPIGVTSLFPLALYPILQIVPSKQISPVY 112

  Fly    96 FSDTVVMFIGGLLIALAIEYSNLHQRIALNTILIVGCSPRRLHFGLVMVTCFISLWISNSAATAM 160
            |.|::|:|:..|::|:|:|.:.||:||||..:..||.....:..|.:.:|.|||.::|::|.||:
Worm   113 FKDSIVLFMCTLIMAMAVEATGLHRRIALKLLTKVGAKQPVMLLGFMCITSFISFFVSDTACTAL 177

  Fly   161 MCPIVKAVLNEME--TQNIFAIYKTQEEEPVEEGDPPHPSTIS----------------MAFYFG 207
            |||...|:|..|.  .|::       :|:..:...||..:|::                .|....
Worm   178 MCPTAVALLMSMSDAVQHL-------KEDHRKPKPPPDDATVAEKLRIDDMTPQDAGFCKALILA 235

  Fly   208 IAYSSSIGGCGTLIGTGTNLTYKGLYDTRFPNSDEKIDFPIFMAYSVP--FVVLV---LIFLTYF 267
            .|::|.|||...:..||.||.::.....|:|.....:.:..:|.:::|  ||.|:   :|.:.||
Worm   236 CAHASLIGGTAIITSTGPNLVFRENIHKRYPEGQVTMTYLQWMVFAIPPMFVYLLASYIILVCYF 300

  Fly   268 SLQVTHMGLFRPNSKIGQEVKKGAESQDVVKDVIKQRKAELGPMSCHEIQVGLLFVLMIFLLFTR 332
            ....|....|...||....:||      :::..|:....:||.:|..|..|.:.|:|:|....:|
Worm   301 MGPSTFARWFERPSKEEAHLKK------LIEKNIQTMYEDLGDVSWGEKSVFVFFILLIGSWISR 359

  Fly   333 KPGFFPGWADFL-NAKAIGSGPPVFFATILLFALPTQYTFFKYCCGKAPF-PGQTLDACLSWVYC 395
            .|||.|||.|.| :...|.........:.:||..|           |.|| |...:...|.|...
Worm   360 DPGFTPGWGDLLPHRNFISDSVSGVLISCILFVWP-----------KDPFDPIDPMAPILKWTDM 413

  Fly   396 QKYTPFGLAFLLGGGFALAEGSRVSGMAKML--GESLAFAGEMHSVLVISMCIIISLFCTAFASN 458
            :....:....|:|.|:|::||...||:::::  |....|.|.....|.:::..|| :..|.||||
Worm   414 KSKFSWSCTLLIGAGYAISEGVDKSGLSRLISCGMKNIFVGMSSLPLQLTVTTII-VIMTEFASN 477

  Fly   459 VAICNILIPIFSEMALAIEVHPMKLTFPAALACSLAFHLPVSTPPNAIISGFTGLKTKYMAIAGI 523
            |:..:|.|||...:|.::.|||:.|..|..:|||.||.||:||||||::.....:....|.:.|.
Worm   478 VSTGSIFIPISLGVAESMGVHPLYLALPTTVACSFAFMLPISTPPNAVVYDTKVISMVEMIVCGF 542

  Fly   524 LPTCWAFLCLLFTG---TVWTMLIY 545
            |..   ..|:|.|.   ..||..|:
Worm   543 LLN---IACILITSLNMNTWTYFIF 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33934	NP_001163660.1	dass	45..540	CDD:273267	153/524 (29%)
CG33934	NP_001163660.1	ArsB_NhaD_permease	52..524	CDD:304373	148/498 (30%)
nac-2	NP_001254976.1	CitT	43..564	CDD:223547	159/543 (29%)
nac-2	NP_001254976.1	ArsB_NhaD_permease	72..552	CDD:304373	151/507 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159149
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57284
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000298
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101290
Panther	1	1.100	-	-	O	PTHR10283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X273
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850