DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment His2A:CG33859 and h2ax

DIOPT Version :9

Sequence 1:	NP_001027376.1	Gene:	His2A:CG33859 / 3772139	FlyBaseID:	FBgn0053859	Length:	124	Species:	Drosophila melanogaster
Sequence 2:	NP_957367.1	Gene:	h2ax / 394048	ZFINID:	ZDB-GENE-040426-987	Length:	142	Species:	Danio rerio

Alignment Length:	125	Identity:	110/125 - (88%)
Similarity:	117/125 - (93%)	Gaps:	1/125 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGRGK-GGKVKGKAKSRSDRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLE 64
            |||||| |||.:.|||:||.||||||||||:||||||||||||||||||||||||:|||.||:||
Zfish     1 MSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILE 65

  Fly    65 LAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKKA 124
            ||||||||||||||||||||||:||||||||||.||||||||||||||||||||||.:.|
Zfish    66 LAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTGQAA 125

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
His2A:CG33859	NP_001027376.1	H2A	16..121	CDD:197711	96/104 (92%)
His2A:CG33859	NP_001027376.1	H2A	16..119	CDD:238029	94/102 (92%)
h2ax	NP_957367.1	PTZ00017	1..121	CDD:185399	107/119 (90%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22		14/20 (70%)
		H2A	6..120	CDD:238029	101/113 (89%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	123..142		1/3 (33%)
		[ST]-Q motif	139..140
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	144	1.000	Domainoid score	I4548
eggNOG	1	0.900	-	-		E1_COG5262
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3500
OMA	1	1.010	-	-		QHG53554
OrthoDB	1	1.010	-	-		D607367at33208
OrthoFinder	1	1.000	-	-		FOG0000046
OrthoInspector	1	1.000	-	-		mtm6415
orthoMCL	1	0.900	-	-		OOG6_100077
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X55
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.780