Protein Alignment Meltrin and Adamdec1

DIOPT Version :10

• Sequence 1: NP_001027575.1
• Gene: Meltrin / 3772109
• FlyBaseID: FBgn0265140
• Length: 1407
• Species: Drosophila melanogaster
• Sequence 2: NP_067450.1
• Gene: Adamdec1 / 58860
• MGIID: 1917650
• Length: 467
• Species: Mus musculus
• Alignment Length: 476
• Identity: 125/476 - (26%)
• Similarity: 202/476 - (42%)
• Gaps: 73/476 - (15%)

  Fly    47 EFSTYTVIRPQ---------VEHGRTKRSLLTTLDATDGLHTPQISLSYTHEGKRVVVDLQRNDL 102
            |...:.::||:         :|:.:|:|.      ..:..:.|::.......|:.:|..|:|
Mouse    38 ELKPHEIVRPKKLPISQKRGLENNQTERY------GKEEKYAPEVQYQIILNGEEIVFHLKR--- 93

  Fly   103 LLPNSHFLRYQNASRGATPGHVVTTFTKTEVDLCHYQGHIRGKPESVVALSTCDGALDGIVIDGR 167
               ..|.|.........:|....:|....:|..|:|:|||:....|:..:||||| |.|
Mouse    94 ---TKHLLGPDYTETSYSPRGEESTRHSQDVKPCYYEGHIQNARGSLARISTCDG-LRG------ 148

  Fly   168 QTYFIHPHIDGRGRLQDDHYLLK--QADMHPTNATCGYDNHRDDHSHDYEKADGDNGLGGGIPSL 230
              ||.|         :|..|.:|  |:.....:|...|.....|..||.:.
Mouse   149 --YFTH---------RDQRYQIKPLQSTDEGEHAVLPYSWKGQDTVHDKDA-------------- 188

  Fly   231 PLRLDGGEFSRTLLRKRRQADDSSQLIRGPYNANKYSSYVELVIVVDNKVYKNFQENTKKVHQYC 295
                     .:.::|||.....|..|.....:..:...|:.|.:|:||..||.:..|..::..:.
Mouse   189 ---------EKQVVRKRSHLRTSRSLKNPNEDLLQGQKYIGLFLVLDNAYYKLYNGNVTQMRTFL 244

  Fly   296 KGIANIINALYVPLNIFVALVGVVIWNESNEIEFSSDGDLTLRNFLNYRSTKL---VLDHPNDNA 357
            ..:.|::|.:|..:||.|:|||:.||::.::|:...:...|..:|:.:..:.|   :.:|    |
Mouse   245 FKVLNLLNMIYKTINIQVSLVGMEIWSDQDKIKVEPNLGATFTHFMRWHYSNLGKRIHNH----A 305

  Fly   358 QLLTKENFAGGVVGKALKGPICTYEYSGGVSMQHSPNPAMVATTMAHEMGHNFGMEHDTSDCHCR 422
            |||:..:|..|.||.|.....||......:..:...|.|:|| .|:||:||..||:.......|.
Mouse   306 QLLSGASFRHGRVGMAAGNSFCTTSSVSVIEAKKKNNVALVA-LMSHELGHALGMKDVPYYTKCP 369

  Fly   423 DEKCVMAASSTSFIPVNWSSCSIDQLTIAFSRGMNYCLRNKPE-RLFESPTCGNGFVEPGEQCDC 486
            ...|||....:|..|.::|:.|........|.....||...|: :....|||||..::.||:|||
Mouse   370 SGSCVMNQYLSSKFPKDFSTVSRSHFQGFLSSRNARCLLLAPDPKNIIKPTCGNQVLDVGEECDC 434

  Fly   487 GLPEHCENACCNAQTCMLHSK 507
            |.||.|.|.||...||.|.|:
Mouse   435 GSPEECTNLCCEPLTCRLKSQ 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Meltrin	NP_001027575.1	Pep_M12B_propep	53..174	CDD:460254	30/129 (23%)
		ZnMc_adamalysin_II_like	269..462	CDD:239797	57/195 (29%)
		Disintegrin	479..554	CDD:459709	16/29 (55%)
		ACR	558..701	CDD:214743
		PHA03247	<823..1261	CDD:223021
		PHA03247	<1220..1392	CDD:223021
Adamdec1	NP_067450.1	Pep_M12B_propep	43..171	CDD:460254	35/157 (22%)
		Reprolysin	217..411	CDD:426256	57/198 (29%)
		Disintegrin	427..>460	CDD:471982	16/29 (55%)