DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Meltrin and F27D9.7

DIOPT Version :9

Sequence 1:	NP_001027575.1	Gene:	Meltrin / 3772109	FlyBaseID:	FBgn0265140	Length:	1407	Species:	Drosophila melanogaster
Sequence 2:	NP_509295.3	Gene:	F27D9.7 / 185019	WormBaseID:	WBGene00017865	Length:	386	Species:	Caenorhabditis elegans

Alignment Length:	334	Identity:	65/334 - (19%)
Similarity:	133/334 - (39%)	Gaps:	76/334 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 VELVIVVDNKVYKNFQENTKKVHQYCKGIANIINALYVPLNIFVALVGVVIWNESNEIEFSSDGD 334
            :..:|.:|:.:.:.:..:..::......:.:.:|..:.||||.::::.::....:|
Worm    49 ITFLIGIDSAMTRYYNYDEARIRSAMIVLMHTVNQYFYPLNIRLSIIDILPVKGTN--------- 104

  Fly   335 LTLRNFLNYRSTKL-VLDHPNDNAQLLTKENFAGGVVGKALKGPICTYEYSGGVSMQHS------ 392
            :.|.:|::::..:. :::|   :..:|.:.|:.||:.            ||.|:..::|
Worm   105 MGLDDFISWKKEQQNLIEH---DVTVLLRHNYEGGIA------------YSNGICSKNSLMISGF 154

  Fly   393 -PNPAM-VATTMAHEMGHNFGMEH-DTSDCHCR---DEKCVMAASSTSFIPVNWSSCSIDQLTIA 451
             |:..| .|....|::.|..|:.| ..:.|.|.   :.:|:..:        .:..||:.::...
Worm   155 LPDATMNNAWVFMHQLAHVIGLTHKQQTKCECNTAINGRCLKLS--------GFPECSVQEMVDK 211

  Fly   452 FSRGMNYCLRNKPERLFES---------PTCGNGFVEPGEQCDCGLPEHCENACCNAQTCMLHSK 507
            .|.  :.||..:.....::         |.||||..|..|:||||....|:|..|:|..|....:
Worm   212 LSN--SSCLIQESPSFAKNTVVPKKGSLPVCGNGLQEDEEECDCGPERFCDNILCDAVKCRFIVQ 274

  Fly   508 NATCAT----------------GECCDLTTCRPKLAGSACRE--AENECDLPEYCTGESEYCPAD 554
            .|...|                |:.| |.:....|..:..||  .:|..|:......:.|..|..
Worm   275 KAYLTTFIPLGFAFIAFVILLFGKYC-LCSLFASLRNTGHREQMEKNRGDIENLNDVDVEQAPVR 338

  Fly   555 V-FRRDTEP 562
            : ..|:.||
Worm   339 MRVSRNEEP 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Meltrin	NP_001027575.1	Pep_M12B_propep	64..174	CDD:279848
		Reprolysin	269..464	CDD:279729	34/206 (17%)
		ZnMc_adamalysin_II_like	269..462	CDD:239797	34/204 (17%)
		Disintegrin	479..555	CDD:278623	23/93 (25%)
		ACR	558..701	CDD:214743	3/5 (60%)
F27D9.7	NP_509295.3	Reprolysin	56..218	CDD:366632	31/195 (16%)
F27D9.7	NP_509295.3	Disintegrin	246..>272	CDD:385688	11/25 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3607
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162519at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11905
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920