| Sequence 1: | NP_001027575.1 | Gene: | Meltrin / 3772109 | FlyBaseID: | FBgn0265140 | Length: | 1407 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_031425.2 | Gene: | Adam10 / 11487 | MGIID: | 109548 | Length: | 749 | Species: | Mus musculus |
| Alignment Length: | 632 | Identity: | 145/632 - (22%) |
|---|---|---|---|
| Similarity: | 232/632 - (36%) | Gaps: | 155/632 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 50 TYTVIRPQVEHGRTKRSLLTTLDATDGLHTPQ-ISLSYTHEGKRVVVDLQRNDLLLPNSHFLRYQ 113
Fly 114 NASRGATPGHVVTTFTKTEVDLCHYQGHIRGKPESVVALSTCDGALDGIVIDGRQTYFIHP---H 175
Fly 176 IDGRGRLQDDHYLLKQADMHPTNATCGYDNHRDD--HSHDYEKADGDNGLGGGIPSLPLRLDGGE 238
Fly 239 FSRTLLRK---------------RRQADDSSQLIRGPYNANKYSSYVELVIVVDNKVYKNFQENT 288
Fly 289 KKVHQYCKGIANIINALYVPLNIFVALVGVVIWNESNEIEFSSD----------GDLTLRNFLNY 343
Fly 344 RSTKLVLDHPNDN---AQLLTKENFAGGVVGKA-------LKGPICTYE--YSGG---------V 387
Fly 388 SMQ----HSPNPAMVATTMAHEMGHNFGMEHDT-SDCHCRDEK---------CVMAASSTSFIPV 438
Fly 439 N---WSSCSIDQLTIAFSRGMNYCLRNKPERLFESPTCGNGFVEPGEQCDCGLPEHCENACC--- 497
Fly 498 ---NAQTCMLH-SKNATCATGECCDLTTCRPKLAGSACREAENECDLPEYCTGESEYCPAD---- 554
Fly 555 ---VFRRDTEPCDGGQAYCFHGTCRSHS-NQCRTLWGPTGDNSEHCY 597 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Meltrin | NP_001027575.1 | Pep_M12B_propep | 64..174 | CDD:279848 | 22/110 (20%) |
| Reprolysin | 269..464 | CDD:279729 | 56/242 (23%) | ||
| ZnMc_adamalysin_II_like | 269..462 | CDD:239797 | 56/240 (23%) | ||
| Disintegrin | 479..555 | CDD:278623 | 26/89 (29%) | ||
| ACR | 558..701 | CDD:214743 | 11/41 (27%) | ||
| Adam10 | NP_031425.2 | Pep_M12B_propep | 46..146 | CDD:279848 | 26/123 (21%) |
| Cysteine switch. /evidence=ECO:0000305 | 171..178 | 3/12 (25%) | |||
| ZnMc_TACE_like | 221..460 | CDD:239798 | 56/251 (22%) | ||
| Reprolysin_2 | 241..445 | CDD:290307 | 50/211 (24%) | ||
| DISIN | 467..546 | CDD:214490 | 24/80 (30%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 705..749 | ||||
| SH3-binding. /evidence=ECO:0000255 | 709..716 | ||||
| SH3-binding. /evidence=ECO:0000255 | 723..729 | ||||
| Interaction with AP2A1, AP2A2 and AP2M1. /evidence=ECO:0000269|PubMed:23676497 | 735..749 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D162519at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.920 | |||||