DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Meltrin and ADAM10

DIOPT Version :9

Sequence 1:NP_001027575.1 Gene:Meltrin / 3772109 FlyBaseID:FBgn0265140 Length:1407 Species:Drosophila melanogaster
Sequence 2:NP_001101.1 Gene:ADAM10 / 102 HGNCID:188 Length:748 Species:Homo sapiens


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MeltrinNP_001027575.1 Pep_M12B_propep 64..174 CDD:279848
Reprolysin 269..464 CDD:279729
ZnMc_adamalysin_II_like 269..462 CDD:239797
Disintegrin 479..555 CDD:278623
ACR 558..701 CDD:214743
ADAM10NP_001101.1 Pep_M12B_propep 46..156 CDD:396235
Cysteine switch. /evidence=ECO:0000250 171..178
ZnMc_TACE_like 220..459 CDD:239798
DISIN 466..545 CDD:214490
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 704..748
SH3-binding. /evidence=ECO:0000255 708..715
SH3-binding. /evidence=ECO:0000255 722..728
Interaction with AP2A1, AP2A2 and AP2M1. /evidence=ECO:0000250|UniProtKB:O35598 734..748
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D162519at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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