Protein Alignment sotv and Extl1

DIOPT Version :10

• Sequence 1: NP_725536.1
• Gene: sotv / 3772101
• FlyBaseID: FBgn0029175
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001101455.1
• Gene: Extl1 / 313610
• RGDID: 1309572
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 739
• Identity: 215/739 - (29%)
• Similarity: 338/739 - (45%)
• Gaps: 142/739 - (19%)

  Fly    32 YGLLVIVALCAGFLLWDLSSSPRDGFFHGKRDSHTLILDLEHIQELA---VNPEAEQR-----AR 88
            :.||:|:   .|.....|:.|||.  ..|:.......||...:|..:   .|||.:.:     :|
  Rat    15 FWLLLIL---LGVFPLRLAVSPRP--LPGRSQGWPRWLDATFLQSFSQPETNPEEDVQQLPRVSR 74

  Fly    89 NVNCTFWDCLNIYKCEHDRLKVYIYPLQEFVDEQSDKTATTLSSEYFQILEAVLKSRYYTSNPNE 153
            ..:||:..|.:..||....||::::         |....||.:..  :||:::..||||..:|.|
  Rat    75 GSSCTWGACFDTSKCRGKVLKIFVH---------SAAGPTTEAQR--RILDSLEGSRYYALSPAE 128

  Fly   154 AC--LFLPSLDLLNQNVFDKHLAGAALASLDFWDRGANHIIFNMLPG------------GAPSYN 204
            ||  |||||.|          ..||.......|:.|.||::.::.|.            .:||
  Rat   129 ACLLLFLPSQD----------RRGACGPLPPNWNGGRNHLVLSLYPAPCTRLGQAMVAEASPS-- 181

  Fly   205 TVLDVNTDNAIIFGGGFDSWSYRPGFDVAIPV---------WSPRLVRQHA---HATAQRKFLLV 257
              ||:                :|||||||:|.         .:|..:::|.   .||     |:.
  Rat   182 --LDI----------------FRPGFDVALPYLPEAHPLKGGAPGSLQRHGPQPGAT-----LVA 223

  Fly   258 VAQLNILPRFVRTLRELSLAHSEQLLLLGACENLDLTMRCPLSQHHK-----SLEYP-RLLSRGK 316
            ||:       .|....::..|:.               .||..::.:     ...|| .:|....
  Rat   224 VAE-------ERGRWRITTTHAS---------------ACPWDRNCEQDPGPQQTYPGEILPNVT 266

  Fly   317 FCLL-GRSLRMGQPDLVEIMSQHCIPVIAVDNYVLPFEDVIDWSLASVRIRENELHSVMQKLKAI 380
            |||: |.  |......::.:...||||:....:.|||.:||||:.|::...|.....|:..|:.:
  Rat   267 FCLIPGH--RSATSCFLQALQAGCIPVLLSPRWELPFSEVIDWTKAAIVADERLPLQVLAALREM 329

  Fly   381 SSVKIVEMQKQVQWLFSKYFKDLKTVTLTALEVLESRIFPLRARSSRQWN----------TIDTN 435
            ...:::.:::|.|:|::.||..::.|..|.||:::.||:...|..|..||          |..|:
  Rat   330 LPSRVLALRQQTQFLWTAYFSSVEKVVHTTLEIIQDRIWGASAHPSLMWNSPPGALLALPTFSTS 394

  Fly   436 ARS-TFNPLFLPSLAPKSQGFTAVILTYDRVESLFLLIQKLAVVPSLQSILVIWNNQKKSPPHLS 499
            .:. .|..|.|.| :|.| .|:|||......||...|||::|.......||::||::|..|   .
  Rat   395 LQDFPFYHLQLGS-SPGS-SFSAVIWVGVSEESPPKLIQEVAGSRHCAQILILWNSEKPPP---D 454

  Fly   500 TFPSISKPLKIRQTKENKLSNRFYPYPEIETEAILTIDDDIIMLTTDELDFGYEVWREFPDHIVG 564
            .:|..:.||.:.: ...|:|:||:.|..|.|..||::|.. ..|:|.|:||.:.||:.||:.:||
  Rat   455 RWPKTAVPLTVIE-GHRKVSDRFFLYSNISTNVILSLDAQ-STLSTSEVDFAFVVWQSFPERMVG 517

  Fly   565 FPSRIHVWENVTMRWHYESEWTNQISMVLTGAAFHHKYWSHMYTHAMPGDIKDWVDEHMNCEDIA 629
            |.:..|.|:.....|.|.:|..|:.|||||.|||:|:|:..::||::|..::...||...|.||.
  Rat   518 FVTWSHFWDEARQGWGYSAEMANEFSMVLTTAAFYHRYYHTLFTHSLPKALRSIADETPTCVDIL 582

  Fly   630 MNFLVANITNNPPIKVTPRKKFKCPECTNTEMLSADLNHMRERSA----CIDRFSKIYGRMPLRT 690
            ||||||.:|..|||||...::.:    ....|.|.....:.|..|    ||:|.:...|.|||.:
  Rat   583 MNFLVATVTKLPPIKVPYSRQHQ----EAAPMASEGPRPVPEPQALDQDCINRLAAGLGHMPLVS 643

  Fly   691 VEFRADPVLFRDNFPDKLKRYNDI 714
            ...|.|||||:|....:.|:|..:
  Rat   644 SRVRLDPVLFKDPVSVQRKKYRSL 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sotv	NP_725536.1	Exostosin	106..380	CDD:397245	74/306 (24%)
		Glyco_transf_64	455..696	CDD:430488	89/244 (36%)
Extl1	NP_001101455.1	Exostosin	108..329	CDD:397245	69/281 (25%)
		Glyco_transf_64	413..649	CDD:430488	89/244 (36%)