Protein Alignment sotv and EXTL2

DIOPT Version :10

• Sequence 1: NP_725536.1
• Gene: sotv / 3772101
• FlyBaseID: FBgn0029175
• Length: 717
• Species: Drosophila melanogaster
• Sequence 2: NP_001248370.1
• Gene: EXTL2 / 2135
• HGNCID: 3516
• Length: 338
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 96/307 - (31%)
• Similarity: 150/307 - (48%)
• Gaps: 57/307 - (18%)

  Fly   408 LTAL--EVLESRIFPLRARSSRQWNTIDTNARSTFNPLFLPSLAPKSQGFTAVILTYDRVESLFL 470
            ||||  .|.|.::..||       ..|.:..:||.:            .||.::.||:|.:.|..
Human    44 LTALLPSVKEDKMLMLR-------REIKSQGKSTMD------------SFTLIMQTYNRTDLLLK 89

  Fly   471 LIQKLAVVPSLQSILVIWNN-QKKSPPHLSTFPSISK---PLKIRQTKENKLSNRFYPYPEIETE 531
            |:.....||:|..::|:||| .:|:|..|  :.|:..   |:..:|...|::.||...:||:||.
Human    90 LLNHYQAVPNLHKVIVVWNNIGEKAPDEL--WNSLGPHPIPVIFKQQTANRMRNRLQVFPELETN 152

  Fly   532 AILTIDDDIIMLTTDELDFGYEVWREFPDHIVGFPSRIHVWENVTMRWHYESEWT-------NQI 589
            |:|.:||| .:::|.:|.|.:.||::|||.||||..|.||..:..:..:...|..       :|.
Human   153 AVLMVDDD-TLISTPDLVFAFSVWQQFPDQIVGFVPRKHVSTSSGIYSYGSFEMQAPGSGNGDQY 216

  Fly   590 SMVLTGAAFHHKYWSHMYTHAMPGDIKDWVDEHMNCEDIAMNFLVA-NITNNPPIKVTPRKKFKC 653
            ||||.||:|.:..:..:: ...|..:...:|:..||:||||||::| :|.....|.|.|
Human   217 SMVLIGASFFNSKYLELF-QRQPAAVHALIDDTQNCDDIAMNFIIAKHIGKTSGIFVKP------ 274

  Fly   654 PECTNTEMLSADLN-----------HMRERSACIDRFSKIYGRMPLR 689
               .|.:.|..:.|           |..:||.||::...||..||||
Human   275 ---VNMDNLEKETNSGYSGMWHRAEHALQRSYCINKLVNIYDSMPLR 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sotv	NP_725536.1	Exostosin	106..380	CDD:397245
		Glyco_transf_64	455..696	CDD:430488	85/258 (33%)
EXTL2	NP_001248370.1	Glyco_transf_64	74..325	CDD:430488	85/258 (33%)