Protein Alignment kay and CREB5

DIOPT Version :9

• Sequence 1: NP_001027577.2
• Gene: kay / 3772082
• FlyBaseID: FBgn0001297
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_016868296.1
• Gene: CREB5 / 9586
• HGNCID: 16844
• Length: 537
• Species: Homo sapiens
• Alignment Length: 456
• Identity: 97/456 - (21%)
• Similarity: 161/456 - (35%)
• Gaps: 142/456 - (31%)

  Fly   189 NTTAAATTSTTATSAAAGSDNNHSDNFAMDASEIATFLANELFLQQLGNFETGQSVLTLTTPTLT 253
            |....|.|.......::....||..|               :.:||........||:     |..
Human   132 NAVGGAMTGPGTHQLSSARLPNHDTN---------------VVIQQAMPSPQSSSVI-----TQA 176

  Fly   254 PTTTRNIEDTLGHL-----LSDTQTDRVAGCAGFAVPKVLPNAIDVLGMGIPT--GVSS--LPLQ 309
            |:|.|.|....|.|     |.:.|...:..    ::|..|||         ||  |.|:  :|::
Human   177 PSTNRQIGPVPGSLSSLLHLHNRQRQPMPA----SMPGTLPN---------PTMPGSSAVLMPME 228

  Fly   310 QTFDLS---LG-QGSESEDSNAS------YNDTQMNEEQDTTDTSSAHTDSTSYQAGHI--MAGS 362
            :...::   :| ||....:..||      :::.:|..:...|...:|.::......||:  |.||
Human   229 RQMSVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNMNTMGHMMEMMGS 293

  Fly   363 --------------------------------------------VNGGGVNNFSNVLAAVSSSRG 383
                                                        .|....::.|::.|..:..:.
Human   294 RQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQT 358

  Fly   384 S----------ASVGSSNANTSNT----PARRGGGRRPNRSTNMTPEEEQKRAVRRERNKQAAAR 434
            |          |.|..:......|    |.:..|||| .|..:..|:|.:::.:  |||:.||.|
Human   359 SPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRR-RRVVDEDPDERRRKFL--ERNRAAATR 420

  Fly   435 CRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYLLATHR----ATCQKIRSDMLSV 495
            ||::|......|.::.|:|.:....::.|:.:|.|...||:.||.||:    ...||
Human   421 CRQKRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLKQLLLTHKDCPITAMQK-------- 477

  Fly   496 VTCNGLIAPAGLLSAGSSGSGASS-----HHNHNSNDSSNGTITGMDATLN--STGRSNSPLDLK 553
             ...|.::|..  |..:|...|.|     .||..:..||...:.| .:||:  :|.|:    ||.
Human   478 -ESQGYLSPES--SPPASPVPACSQQQVIQHNTITTSSSVSEVVG-SSTLSQLTTHRT----DLN 534

  Fly   554 P 554
            |
Human   535 P 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kay	NP_001027577.2	bZIP_Fos	420..481	CDD:269869	19/60 (32%)
		coiled coil	421..480	CDD:269869	19/58 (33%)
CREB5	XP_016868296.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1414
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R103
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840