Protein Alignment kay and SKO1

DIOPT Version :10

• Sequence 1: NP_001027577.2
• Gene: kay / 3772082
• FlyBaseID: FBgn0001297
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_014232.1
• Gene: SKO1 / 855554
• SGDID: S000005111
• Length: 647
• Species: Saccharomyces cerevisiae
• Alignment Length: 703
• Identity: 134/703 - (19%)
• Similarity: 255/703 - (36%)
• Gaps: 190/703 - (27%)

  Fly    64 PTQPAYQQSQ-------SVAHNAFPLRSSSNNYGHVASSAYAASSGSHNSNNAAAMAAVCQMQNF 121
            |.:.::..|:       :::|.:.|...|.||  ..::....:...:|:.|:.
Yeast    22 PFEQSFASSKKALSLPGTISHPSLPKELSRNN--STSTITQHSQRSTHSLNSI------------ 72

  Fly   122 FNQQQQQQQQLEFNNNCMPINYYQQQQQQHYPSESQSSASGWNPETPGQAQ----LALT------ 176
              .::.....:..|:|   .|..::......|.:.:.:.......|||.::    |.|:
Yeast    73 --PEENGNSTVTDNSN---HNDVKKDSPSFLPGQQRPTIISPPILTPGGSKRLPPLLLSPSILYQ 132

  Fly   177 --ATT-----CNTTAAATCNTTAAATTSTTA-----TSAAAGSD------------NNHSDNFAM 217
              :||     .::.:.:..|.:|...:||:.     :|:.:|:.            :|..:.|..
Yeast   133 ANSTTNPSQNSHSVSVSNSNPSAIGVSSTSGSLYPNSSSPSGTSLIRQPRNSNVTTSNSGNGFPT 197

  Fly   218 DASEIATFLANELFLQQLG------NFETGQSVLTLTT----PTL------TPTTTRNIEDTL-- 264
            :.|::..||.|   |.:.|      |..||.:...||.    |.|      |.|.::|:..::
Yeast   198 NDSQMPGFLLN---LSKSGLTPNESNIRTGLTPGILTQSYNYPVLPSINKNTITGSKNVNKSVTV 259

  Fly   265 -----GHLLSDTQTDRVAGCAGFAVPKVLPNAIDVLGMGIPTGV------SSLPLQQTFDLSLGQ 318
                 .|...:.....|.|      ..:.|....:|.:. .|||      .|.|...|.|.::
Yeast   260 NGSIENHPHVNIMHPTVNG------TPLTPGLSSLLNLP-STGVLANPVFKSTPTTNTTDGTV-- 315

  Fly   319 GSESEDSNASYN-DTQMNEEQDTTDTSSA--HTDSTSYQAGHIMAGSVNGGGVNN--------FS 372
            .:...:||.|.| .|:...:.|.....:|  |:.....:..::.....|....||        .|
Yeast   316 NNSISNSNFSPNTSTKAAVKMDNPAEFNAIEHSAHNHKENENLTTQIENNDQFNNKTRKRKRRMS 380

  Fly   373 NVLAAVSSSRGSASVGSSNANTSNTPARRGGGRRPNRSTNMT----PEEEQKRAVRRERNKQAAA 433
            :..:...:||.: |:...|:..:..||::........|.|:|    .|:|:||....|||:.||:
Yeast   381 STSSTSKASRKN-SISRKNSAVTTAPAQKDDVENNKISNNVTLDENEEQERKRKEFLERNRVAAS 444

  Fly   434 RCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYLLATHRATCQKIRSDMLSVV-- 496
            :.|||:.:...::..:::..|.                   ||             .|:..|:
Yeast   445 KFRKRKKEYIKKIENDLQFYES-------------------EY-------------DDLTQVIGK 477

  Fly   497 TCNGLIAPAGLLSAGSSGSGASSHHNHNSNDSSNGTITGMDATLNST-GRSNSPLDLKPAANIDS 560
            .| |:|.        ||.|.:..:.|.::..||:...|.:.|.|.|: .||:....:...:|:..
Yeast   478 LC-GIIP--------SSSSNSQFNVNVSTPSSSSPPSTSLIALLESSISRSDYSSAMSVLSNMKQ 533

  Fly   561 LLMHI----------KDEPLDGAIDSGSSLDQD-GPPPSKRITLPPMSTMPHVHLSTILTPTGAS 614
            |:...          :|: :||..|   |.::| ....|:....|.:::.|.:........:||:
Yeast   534 LICETNFYRRGGKNPRDD-MDGQED---SFNKDTNVVKSENAGYPSVNSRPIILDKKYSLNSGAN 594

  Fly   615 ---SGSLQTPITSTAPGGFGSAFPVTSNGSSINNINSIGNNMNSPT--LNAHN 662
               |.:....:.::|.....|.:.||         |.:..|.||.|  .|.|:
Yeast   595 ISKSNTTTNNVGNSAQNIINSCYSVT---------NPLVINANSDTHDTNKHD 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kay	NP_001027577.2	bZIP_Fos	420..481	CDD:269869	13/60 (22%)
		coiled coil	421..480	CDD:269869	12/58 (21%)
SKO1	NP_014232.1	Aft1_HRA	<196..>228	CDD:371723	9/34 (26%)
		bZIP_ATF2	431..482	CDD:269835	17/83 (20%)
		coiled coil	431..482	CDD:269835	17/83 (20%)