DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kay and ATF3

DIOPT Version :9

Sequence 1:	NP_001027577.2	Gene:	kay / 3772082	FlyBaseID:	FBgn0001297	Length:	755	Species:	Drosophila melanogaster
Sequence 2:	NP_001025458.1	Gene:	ATF3 / 467	HGNCID:	785	Length:	181	Species:	Homo sapiens

Alignment Length:	159	Identity:	45/159 - (28%)
Similarity:	69/159 - (43%)	Gaps:	41/159 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   356 GHIMAGSVNGGGV------------NNFSNVLAAV-----------------SSSRGSASVGSSN 391
            |.:.|..|:...:            .:|:|:...|                 ||:..|.:|....
Human     7 GQVSASEVSASAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTVSDRP 71

  Fly   392 ANTSNTPARRGGGRRPNRSTNMTPEEEQKRAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKR 456
            ...|.|.|            .:.|||::::..||||||.|||:||.::.::|..|.:|.|:||..
Human    72 LGVSITKA------------EVAPEEDERKKRRRERNKIAAAKCRNKKKEKTECLQKESEKLESV 124

  Fly   457 GESMRKEIEVLTNSKNQLEYLLATHRATC 485
            ...::.:||.|.|.|..|.|:|..||.||
Human   125 NAELKAQIEELKNEKQHLIYMLNLHRPTC 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kay	NP_001027577.2	bZIP_Fos	420..481	CDD:269869	25/60 (42%)
kay	NP_001027577.2	coiled coil	421..480	CDD:269869	25/58 (43%)
ATF3	NP_001025458.1	Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	88..110		11/21 (52%)
		bZIP_ATF3	96..149	CDD:269870	21/52 (40%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	114..142		10/27 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1414
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810