DRSC/TRiP Functional Genomics Resources

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Protein Alignment kay and Fosl2

DIOPT Version :9

Sequence 1:NP_001027577.2 Gene:kay / 3772082 FlyBaseID:FBgn0001297 Length:755 Species:Drosophila melanogaster
Sequence 2:NP_032063.2 Gene:Fosl2 / 14284 MGIID:102858 Length:326 Species:Mus musculus


Alignment Length:396 Identity:96/396 - (24%)
Similarity:147/396 - (37%) Gaps:136/396 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   329 YNDTQMNEEQDTTDTSSAHTDSTSYQAGHIMAGSVNGGGVNNFSNVLAAVSSSRGSASVGSSNAN 393
            |.|...|.:..:..:|.:...:.||.:|        |||...|    .......|||.:.:.||.
Mouse     2 YQDYPGNFDTSSRGSSGSPAHAESYSSG--------GGGQQKF----RVDMPGSGSAFIPTINAI 54

  Fly   394 T-----------------SNTPAR--------------------RGG---------GRRPNRSTN 412
            |                 ||...|                    |.|         ||| .|...
Mouse    55 TTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRR-RRDEQ 118

  Fly   413 MTPEEEQKRAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYL 477
            ::||||:||.:||||||.|||:||.||.:.|.:|..|.|:||:....::|||..|...|.:||::
Mouse   119 LSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFM 183

  Fly   478 LATHRATCQKIRSDMLSVVTCNGLIAPAGLLSAGSSGSGASSHHNHNSNDSSNGTITGMDATLNS 542
            |..|...|:               |:|....|..:||.                      .:|..
Mouse   184 LVAHGPVCK---------------ISPEERRSPPTSGL----------------------QSLRG 211

  Fly   543 TGRSNSPLDLKPAANIDSLLMHIKDEPLDGAIDSGSSLDQDGPPPSKRITLPPMSTM-------P 600
            ||.:..|:.:|            ::.|.:.:..|.:.:|:     ::|..:.|:|..       .
Mouse   212 TGSAVGPVVVK------------QEPPEEDSPSSSAGMDK-----TQRSVIKPISIAGGGFYGEE 259

  Fly   601 HVHLSTILTPTGASSGSLQTPITS----TAPGGFGSAFPVTSNGS-------SINNINSIGNNMN 654
            .:|...::|.|.|.     ||.||    |.|.......|.:.:.|       |.::.:...:::|
Mouse   260 PLHTPIVVTSTPAI-----TPGTSNLVFTYPNVLEQESPSSPSESCSKAHRRSSSSGDQSSDSLN 319

  Fly   655 SPTLNA 660
            ||||.|
Mouse   320 SPTLLA 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kayNP_001027577.2 bZIP_Fos 420..481 CDD:269869 29/60 (48%)
coiled coil 421..480 CDD:269869 28/58 (48%)
Fosl2NP_032063.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..39 11/48 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 110..131 10/21 (48%)
Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 126..128 1/1 (100%)
Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 129..136 5/6 (83%)
bZIP_Fos 134..187 CDD:269869 23/52 (44%)
coiled coil 134..186 CDD:269869 23/51 (45%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 193..244 14/89 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 285..326 10/41 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1414
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm44334
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR23351
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R103
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
65.900

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