Protein Alignment kay and CREB1

DIOPT Version :9

• Sequence 1: NP_001027577.2
• Gene: kay / 3772082
• FlyBaseID: FBgn0001297
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001358355.1
• Gene: CREB1 / 1385
• HGNCID: 2345
• Length: 341
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 84/437 - (19%)
• Similarity: 146/437 - (33%)
• Gaps: 125/437 - (28%)

  Fly    44 QQQQQQQAPQQQLRHQQRQLPTQPAYQQSQSVAHNAFPLRSSSNNYGHVASSAYAASSGSHNSNN 108
            :.||...|...:..:||..:..||                       .:|:.|..:...:|.:::
Human     8 ENQQSGDAAVTEAENQQMTVQAQP-----------------------QIATLAQVSMPAAHATSS 49

  Fly   109 AAAMAAVCQMQNFFNQQQQQQQQLEFNNNCMPINYYQQQQQQHYPSESQSSASGWNPETPGQAQL 173
            |..:..|               ||. |...:.::...|..|   ||..||.          |.|
Human    50 APTVTLV---------------QLP-NGQTVQVHGVIQAAQ---PSVIQSP----------QVQ- 84

  Fly   174 ALTATTCNTTAAATCNTTAAATTSTTATSAAAGSDNNHSDNFAMDASEIATFLA---------NE 229
                     |..::|.......:.|..::.|...|:..|.:...|:.:....|:         |:
Human    85 ---------TVQSSCKDLKRLFSGTQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILND 140

  Fly   230 LFLQQLG--NFETGQSVLTLTTPTLTPTT--TRNIEDTLGHLLSDTQTDRVAGCAGFAVPKVLPN 290
            |.....|  ..|..:|....:.|.:|..|  |...:.:.|..::.||        |.|: ::..|
Human   141 LSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQ--------GGAI-QLANN 196

  Fly   291 AIDVLGMGIPTGVSSLPLQQTFDLSLGQGSESEDSNASYNDTQMNEEQDTTDTSSAHTDSTSYQA 355
            ..|        ||..|   ||..::        ::.|:...|.:.:...|||.......|....
Human   197 GTD--------GVQGL---QTLTMT--------NAAATQPGTTILQYAQTTDGQQILVPSNQVV- 241

  Fly   356 GHIMAGSVNGGGVNNFSNVLAAVSSSRGSASVGSSNANTSNTPARRGGGRRPNRSTNMTPEEEQK 420
              :.|.|   |.|..:....|..|:......:.||                |...|....|..:|
Human   242 --VQAAS---GDVQTYQIRTAPTSTIAPGVVMASS----------------PALPTQPAEEAARK 285

  Fly   421 RAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVL 467
            |.||..:|::||..||:::.:....|...|..||.:.:::.:|::.|
Human   286 REVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKAL 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kay	NP_001027577.2	bZIP_Fos	420..481	CDD:269869	15/48 (31%)
		coiled coil	421..480	CDD:269869	14/47 (30%)
CREB1	NP_001358355.1	pKID	113..151	CDD:396650	6/37 (16%)
		bZIP_CREB1	285..339	CDD:269838	15/48 (31%)
		coiled coil	286..337	CDD:269838	14/47 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R103
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030