Protein Alignment mus201 and YEN1

DIOPT Version :9

• Sequence 1: NP_001027230.1
• Gene: mus201 / 3772069
• FlyBaseID: FBgn0002887
• Length: 1236
• Species: Drosophila melanogaster
• Sequence 2: NP_010959.2
• Gene: YEN1 / 856764
• SGDID: S000000843
• Length: 759
• Species: Saccharomyces cerevisiae
• Alignment Length: 642
• Identity: 121/642 - (18%)
• Similarity: 238/642 - (37%)
• Gaps: 178/642 - (27%)

  Fly   685 LKSSKIVPKQELIELCDSDDNKNNRLSPNKTPSKNKSIKDF---FETSYVVKRTPDKSQASNETS 746
            |:.|:|..::.:|     |.||:.:.:|      ..:|..:   ||..::  :..|.|..|...|
Yeast    14 LQDSRIPLRKFVI-----DFNKSQKRAP------RIAIDAYGWLFECGFI--QNIDISARSRSRS 65

  Fly   747 PGTPKTPKPFFRKRTPKSGRKRASDANEDSDEEVSPTKRSSKASKSLFE---------------- 795
            ....::|:                |::.||.:|...::..:...|::..
Yeast    66 RSPTRSPR----------------DSDIDSSQEYYGSRSYTTTGKAVINFISRLKELLSLNVEFL 114

  Fly   796 -----PKEPEEEKTVDPEEIIKDAAEALKSQKTSEELQELATNLAQERKELEIERNRQDRMGMSI 855
                 ..:|..::..:.|:          :..|.::.:|..::..|..|..|:..|.:..:..|.
Yeast   115 LVFDGVMKPSFKRKFNHEQ----------NATTCDDEKEYYSSWEQHVKNHEVYGNCKGLLAPSD 169

  Fly   856 SQRMSIDCQELLRLFGIPYIVAPMEAEAQCAFLNATDLTHGTITDDSDIWLFGGRTVYKNFFAQN 920
            .:.:|: .::||.|..|.|::|..|.||||.:|..:......:::|||..:|||..:.||:   :
Yeast   170 PEFISL-VRKLLDLMNISYVIACGEGEAQCVWLQVSGAVDFILSNDSDTLVFGGEKILKNY---S 230

  Fly   921 KHVMEF-----------RAEQIEQTF---------NCNRGK------LIQLACLVGSDYTTGIHG 959
            |...:|           |....:::|         |...||      |:..:.|:|:||..|:.|
Yeast   231 KFYDDFGPSSITSHSPSRHHDSKESFVTVIDLPKINKVAGKKFDRLSLLFFSVLLGADYNRGVKG 295

  Fly   960 IGAVTALEILASFSGQDANGPGICNQSVLQTLIKFRDWWQAHKCSNLPPGS---------SARLA 1015
            :|...:|::...   :|.|           ..::|.|.::.....:|...|         ..||.
Yeast   296 LGKNKSLQLAQC---EDPN-----------FSMEFYDIFKDFNLEDLTSESLRKSRYRLFQKRLY 346

  Fly  1016 LRKKLKNIEL-------------HEGFPSGAVVEAYLAPTIDDNRDAFSWGTPDVESIREFTRKS 1067
            |..|..::||             .||:||...:..|..|.:....|      .:|.|.:......
Yeast   347 LYCKDHSVELFGRNYPVLLNQGSFEGWPSTVAIMHYFHPIVQPYFD------EEVLSDKYINMAG 405

  Fly  1068 FGWTTSKTDDILMPVMKKIN-------EKKIQGSIRNYFTAKSALRV-QQPHVSKRVQLAIDKMS 1124
            .|...:...:.|...::.:|       :|....|:...|..:..|.: :..::.|
Yeast   406 NGHYRNLNFNELKYFLQSLNLPQISSFDKWFHDSMHEMFLLREFLSIDESDNIGK---------- 460

  Fly  1125 GKIDETPEKPKKVT---------RTRRAKAAPPTDDDLAIADVA--TKAARPKRGKRKAAPESVV 1178
            |.:..|.||...:.         :.|.....|    ::.|:..:  .::..|.|.|.....:..:
Yeast   461 GNMRITEEKIMNIDGGKFQIPCFKIRYTTFLP----NIPISSQSPLKRSNSPSRSKSPTRRQMDI 521

  Fly  1179 LDGELPSTSQSIPK---PEKCPRIPSSVEV--IPQREKDLEQMRLNKAKAAEILKNS 1230
            :  |.|: |..:||   |:..|.:....|.  :.|:||:.:..:.||::..:  ||:
Yeast   522 M--EHPN-SLWLPKYLIPQSHPLVIQYYETQQLIQKEKEKKGKKSNKSRLPQ--KNN 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus201	NP_001027230.1	rad2	1..1122	CDD:273166	96/516 (19%)
		PIN_XPG	1..>121	CDD:189038
		PIN_XPG	<814..1084	CDD:189038	67/317 (21%)
		H3TH_XPG	940..1045	CDD:188624	29/132 (22%)
YEN1	NP_010959.2	PIN_YEN1	2..275	CDD:350218	58/303 (19%)
		H3TH_YEN1	286..388	CDD:188626	25/115 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11081
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010