Protein Alignment mus201 and Gen1

DIOPT Version :10

• Sequence 1: NP_001027230.1
• Gene: mus201 / 3772069
• FlyBaseID: FBgn0002887
• Length: 1236
• Species: Drosophila melanogaster
• Sequence 2: NP_001421006.1
• Gene: Gen1 / 298884
• RGDID: 1559792
• Length: 910
• Species: Rattus norvegicus
• Alignment Length: 477
• Identity: 106/477 - (22%)
• Similarity: 190/477 - (39%)
• Gaps: 107/477 - (22%)

  Fly   845 RNRQDRMGMSISQRMSIDCQELLRLFGIPYIVAPMEAEAQCAFLNATDLTHGTITDDSDIWLFGG 909
            ::|..:.|.|..:.:..:|.|:|...|:|::.|..||||.||:|||:....|.:|:|.|.:|:|.
  Rat    99 KSRSQKTGRSHFKSVLRECLEMLECLGMPWVQAAGEAEAMCAYLNASGHVDGCLTNDGDAFLYGA 163

  Fly   910 RTVYKNFFAQNK--HVMEFRAEQIEQTFNCNRGKLIQLACLVGSDY-TTGIHGIGAVTALEILAS 971
            :|||:||....|  ||..:....|:.....:|..|:.||.|:|.|| ..|:.|:|...||::|..
  Rat   164 QTVYRNFTMNTKDPHVDCYTVSSIKSKLGLDRDALVGLAVLLGCDYLPKGVPGVGKEQALKLLQI 228

  Fly   972 FSGQD--------ANGPG----------ICNQSVLQ-------------TLIKFRDWWQAHKCSN 1005
            ..||.        ...||          :.:.||..             ||.|...:.:.|....
  Rat   229 LKGQSLLQRFNQWTEEPGYSVPQSAAKKVVHCSVCSHPGSPKDHERNGCTLCKSDRYCEPHDYEY 293

  Fly  1006 LPPGSSARLALRKKLKNIELH--------EGFPSGAVVEAYLAPTIDDNR--DAFSWGTPDVESI 1060
            |.|....:....::|..||.:        ||||...|::.:|:   :.|:  ....:..||:...
  Rat   294 LCPCEWHQTDHNRQLNEIENNIKKKACSCEGFPFHEVIQEFLS---NKNKLLKPIRYQRPDLLLF 355

  Fly  1061 REFTRKSFGWTTSKTDDILMPVMKKIN--EKKIQGSIRNYFTAKSALRVQQPHVSKRV-QLAI-- 1120
            :.||.:...|.:....:.|:.::.:.:  |:|:.....|..   ..:|:.:|.:...| .|.|
  Rat   356 QRFTVQKMEWPSHYACEKLLVLLTRYDMIERKLGRKTSNQL---QPIRIVKPRIRNGVCCLEIEW 417

  Fly  1121 ---------DKMSGKID------------ETPE------KPKKVTRTRRAKA-----------AP 1147
                     |...|.:|            ..||      |.:..|:.::.|:           .|
  Rat   418 EKPEHYSVEDTQPGGLDLLTIEEASLFEAAYPEVVAIYQKQQSETKGKKQKSKDIKIKPKGSHLP 482

  Fly  1148 PTDDDLAIADVAT----KAARPKRGKR---KAAPESVVLDGELPSTSQSIPKPEKC-------PR 1198
            .:||.::...:.|    ..|.||:..:   :.:|:.::.......:..|...||..       ..
  Rat   483 ESDDVISSQSLITLEPISKAFPKQNPKFDLEISPDPILAQESTSPSLSSFVSPENALGLNLQEQL 547

  Fly  1199 IPSSVEVIPQREKDLEQMRLNK 1220
            :||...:..::.||:....:::
  Rat   548 MPSPRTLAVKQTKDVSNFLVSE 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus201	NP_001027230.1	rad2	1..1122	CDD:273166	83/334 (25%)
Gen1	NP_001421006.1	PIN_GEN1	2..206	CDD:350217	38/106 (36%)
		H3TH_StructSpec-5'-nucleases	195..337	CDD:473957	35/144 (24%)
		Chromo_2	397..457	CDD:465841	10/59 (17%)