DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mus201 and crn-1

DIOPT Version :9

Sequence 1:	NP_001027230.1	Gene:	mus201 / 3772069	FlyBaseID:	FBgn0002887	Length:	1236	Species:	Drosophila melanogaster
Sequence 2:	NP_491168.1	Gene:	crn-1 / 171917	WormBaseID:	WBGene00000794	Length:	382	Species:	Caenorhabditis elegans

Alignment Length:	463	Identity:	99/463 - (21%)
Similarity:	170/463 - (36%)	Gaps:	120/463 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   739 SQASNETSPGTPKT--PKPFFRKRTPKSGRKRASDAN-----------EDSDEEVSPTKRSSKAS 790
            ||...:.:|...|.  .|.||       ||..|.||:           :|..:..|....::...
Worm     7 SQVIADNAPSAIKVNEMKAFF-------GRTVAIDASMCLYQFLIAVRQDGSQLQSEDGETTSHL 64

  Fly   791 KSLFEPKEPEEEKTVDPEEIIKDAAEALKS---QKTSEELQELATNLAQERKELEI-ERNRQDRM 851
            ..:........|..|.|..:.......:|.   :|.||...|....|.:.:::.:: |..:.:|.
Worm    65 MGMLNRTVRMFENGVKPVYVFDGKPPDMKGGELEKRSERRAEAEKALTEAKEKGDVKEAEKFERR 129

  Fly   852 GMSISQRMSIDCQELLRLFGIPYIVAPMEAEAQCAFLNATDLTHGTITDDSDIWLFGGRTVYKNF 916
            .:.::::.:.:.:.||.|.|||.:.||.|||||||.|.......||:|:|.|...||...:.::|
Worm   130 LVKVTKQQNDEAKRLLGLMGIPVVEAPCEAEAQCAHLVKAGKVFGTVTEDMDALTFGSTVLLRHF 194

  Fly   917 F---AQNKHVMEFRAEQIEQTFNCNRGKLIQLACLVGSDYTTGIHGIGAVTALEILASFSGQDAN 978
            .   |:...:.||......:....:..:.|.|..|:|.||...|.|:|...|:|::.    |..|
Worm   195 LAPVAKKIPIKEFNLSLALEEMKLSVEEFIDLCILLGCDYCGTIRGVGPKKAVELIR----QHKN 255

  Fly   979 GPGICNQSVLQTLIKFRDWWQAHKCSNLPPGSSARLALRKKLKNIELHEGFPSGAVVEAYLAPTI 1043
                     ::|:::..|.      :..||                 .|.:|.....|.:|.|.:
Worm   256 ---------IETILENIDQ------NKYPP-----------------PEDWPYKRARELFLNPEV 288

  Fly  1044 DDNRDA-FSWGTPDVESIREFT--RKSFGWTTSKTDDILMPVMKKINEKKIQGSIRNYFTAKSAL 1105
            ....:. .:|...|||.:.:|.  .|:|                  ||::|:.::....|::.:
Worm   289 TKPEEVELTWKEADVEGVIQFLCGEKNF------------------NEERIRNALAKLKTSRKS- 334

  Fly  1106 RVQQPHVSKRVQLAIDKMSGKIDETPEKPKKVT----RTRRAKAAPPTDDDLAIADVATKAARPK 1166
                            ...|:||.......|||    .|:|.               |.:|.:.|
Worm   335 ----------------GTQGRIDSFFGNSTKVTCVTAATKRK---------------AEEAEKAK 368

  Fly  1167 RGKRKAAP 1174
            :|.:|..|
Worm   369 KGAKKGGP 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mus201	NP_001027230.1	rad2	1..1122	CDD:273166	85/405 (21%)
		PIN_XPG	1..>121	CDD:189038
		PIN_XPG	<814..1084	CDD:189038	64/279 (23%)
		H3TH_XPG	940..1045	CDD:188624	22/104 (21%)
crn-1	NP_491168.1	PIN_FEN1	4..344	CDD:189037	88/414 (21%)
		fen_arch	22..344	CDD:274717	84/399 (21%)
		H3TH_FEN1-Euk	221..290	CDD:188627	22/104 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094524at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920