Protein Alignment mus201 and Fen1

DIOPT Version :10

• Sequence 1: NP_001027230.1
• Gene: mus201 / 3772069
• FlyBaseID: FBgn0002887
• Length: 1236
• Species: Drosophila melanogaster
• Sequence 2: NP_032025.2
• Gene: Fen1 / 14156
• MGIID: 102779
• Length: 380
• Species: Mus musculus
• Alignment Length: 371
• Identity: 81/371 - (21%)
• Similarity: 146/371 - (39%)
• Gaps: 93/371 - (25%)

  Fly   793 LFEPKEPEEEKTVDPEEIIKDAAEALKSQKTSEELQELATNLAQERKE--LEIERNRQDRMGMSI 855
            :|:.|.|:          :|....|.:|::.:|..::|     |:.:|  :|.|..:..:..:.:
Mouse    84 VFDGKPPQ----------LKSGELAKRSERRAEAEKQL-----QQAQEAGMEEEVEKFTKRLVKV 133

  Fly   856 SQRMSIDCQELLRLFGIPYIVAPMEAEAQCAFLNATDLTHGTITDDSDIWLFGGRTVYKNFFAQN 920
            :::.:.:|:.||.|.||||:.||.||||.||.|......:...|:|.|...||...:.::..|..
Mouse   134 TKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASE 198

  Fly   921 KH---VMEFRAEQIEQTFNCNRGKLIQLACLVGSDYTTGIHGIGAVTALEILASFSGQDANGPGI 982
            ..   :.||...::.|....|:.:.:.|..|:||||...|.|||...|::::
Mouse   199 AKKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLI------------- 250

  Fly   983 CNQSVLQTLIKFRDWWQAHKCSNLPPGSSARLALRKKLKNIELHEGFPSGAVVEAYLAP-TIDDN 1046
                            |.||       |...:..|.......:.|.:......:.:|.| .:|..
Mouse   251 ----------------QKHK-------SIEEIVRRLDPSKYPVPENWLHKEAQQLFLEPEVLDPE 292

  Fly  1047 RDAFSWGTPDVESIREFT--RKSFGWTTSKTDDILMPVMKKINEKK---IQGSIRNYFTAKSALR 1106
            .....|..|:.|.:.:|.  .|.|      :::.:...:|::::.:   .||.:.::|....:|
Mouse   293 SVELKWSEPNEEELVKFMCGEKQF------SEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSL- 350

  Fly  1107 VQQPHVSKRVQLAIDKMSGKIDE-TPEKP-KKVTRT------RRAK 1144
                            .|.|..| .|:.| ||..:|      ||.|
Mouse   351 ----------------SSAKRKEPEPKGPAKKKAKTGGAGKFRRGK 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus201	NP_001027230.1	rad2	1..1122	CDD:273166	70/339 (21%)
Fen1	NP_032025.2	PTZ00217	1..359	CDD:240317	73/348 (21%)
		I-domain	122..253		40/159 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..380		14/69 (20%)
		Interaction with PCNA. /evidence=ECO:0000255|HAMAP-Rule:MF_03140	336..344		2/7 (29%)