Protein Alignment mus201 and BIVM-ERCC5

DIOPT Version :9

• Sequence 1: NP_001027230.1
• Gene: mus201 / 3772069
• FlyBaseID: FBgn0002887
• Length: 1236
• Species: Drosophila melanogaster
• Sequence 2: NP_001191354.2
• Gene: BIVM-ERCC5 / 100533467
• HGNCID: 43690
• Length: 1640
• Species: Homo sapiens
• Alignment Length: 1243
• Identity: 341/1243 - (27%)
• Similarity: 565/1243 - (45%)
• Gaps: 277/1243 - (22%)

  Fly    30 DISIWLHQVVKGFQDNKGSALSNAHLLGLFHRLCKLLYYRVRPVFIFDGCVPQLKRDTIARRQQQ 94
            :|||||:|.:||.:|..|:::.|.|||.|||||||||::|:||:|:|||..|.||:.|:.:|:|:
Human   484 NISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQR 548

  Fly    95 RNKLSNEADRIQALLLQSLAKEKVVQQAL-GKNAELLLKSPVKRPPPAKKNDEDDLFKLPELPAA 158
            ::..|:::.:....||::..|.:.::.|. .|..|.|       |...:...|:||:.||.|...
Human   549 KDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEAL-------PSLTQVRRENDLYVLPPLQEE 606

  Fly   159 SVQDNQDESEQDTSASASDSSFDESTARHSYNSSLQAIDVKSQHFRNLPADVRHEILTDIKETRK 223
            ....:::|.|::.....:    .:...:..:..:.||||::|:.|.:||.:|:||||||:||..|
Human   607 EKHSSEEEDEKEWQERMN----QKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTK 667

  Fly   224 QSSWGRLHE-LPARSDDFCSFQMKRLLKRRAVQESLEQAEQEM----GGHTLTYAELCDFFNEEG 283
            :..  .|.| :|..||||..:|:|.|||:..:.:.:|..::||    .||.....|     :|.|
Human   668 RRR--TLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYE-----DEGG 725

  Fly   284 ILTPTAIEQCTRQISSDEHTRFLLVRDLKKKAMESTKQE--------------VKMEMIEEVPAE 334
            .|.    |..:|::.|::.:.::|::.::.|.:.....|              ||....|::..|
Human   726 FLK----EVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTE 786

  Fly   335 EE-DEKPSTSTKKEAVKSVDLGTEFDEDLAKALSMSMEETKVYDEKDYEYDSDQELRLNRAQTKQ 398
            :| |..|.:.....|:::..||:..:|:|                     :|:     ||.|.:
Human   787 KEPDATPPSPRTLLAMQAALLGSSSEEEL---------------------ESE-----NRRQAR- 824

  Fly   399 LRHAAKGPARAYMIEYGGMNDEEVGNIMEATQFNDTQSLEKLLEITTVPTDMADNSIEEAKLISQ 463
               ....||
Human   825 ---GRNAPA-------------------------------------------------------- 830

  Fly   464 AIEESKQLSQAIEESKKNLNEDK-VEIV---DTDTDSDLEEVMEV----QELDKGKKNLEICVDI 520
            |::|.....:.:...|:.|::|: |::.   |..|.....|.|.:    :..|:|.|
Human   831 AVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLK-------- 887

  Fly   521 TGQADSNDLFADIFEDGEANKIEKTISVEEDDDFIEVKDSEELKLDTEDENKPITNKSIKE---- 581
                         ..||:......|::..      .|..:||....|.:..:| |:...||
Human   888 -------------VRDGKGIPFTATLASS------SVNSAEEHVASTNEGREP-TDSVPKEQMSL 932

  Fly   582 ---SNEVKPFIDEIIEVKDSQEAVPAE------------PN---LKPDLESILNDLKKQTAAVKD 628
               ..|..|..||.: :||.::.:|.|            ||   |.|...:..|.:.|.....:.
Human   933 VHVGTEAFPISDESM-IKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEV 996

  Fly   629 IQ----------------LNVNEEEKPKPK-----------VEISSILDELKVKMADVKNITLDN 666
            ::                |:.::|.|.||.           .|.|||:......:.:|:|:...|
Human   997 LEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFN 1061

  Fly   667 VKLSNSVPIILSSDDESTLKSSKIVPKQELIELCDSDDNKNNRLSPNKTPS-KNKSIKDFFETSY 730
            .|...:  .:.:..::.|.:|:    .|:||.:       ...:.|.:..| :::|...|.|...
Human  1062 AKEHEN--FLETIQEQQTTESA----GQDLISI-------PKAVEPMEIDSEESESDGSFIEVQS 1113

  Fly   731 VVKRTPDKSQASNETSPGTPKTPKPFFRKRTPKSGRKRASDANEDSDEEVSPTK--RSSKASKSL 793
            |:        :..|.....|:|.||                .:|..:||:..|:  .:...|:||
Human  1114 VI--------SDEELQAEFPETSKP----------------PSEQGEEELVGTREGEAPAESESL 1154

  Fly   794 FEPKEPEEEKTVDPEEIIKDAAEALKSQK--TSEELQELATNLAQERKELEIERNRQDRMGMSIS 856
            .......::...:|:|..|||.::|...:  ..|||:.|.:||..::..|:.::.:|:|:..:::
Human  1155 LRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVT 1219

  Fly   857 QRMSIDCQELLRLFGIPYIVAPMEAEAQCAFLNATDLTHGTITDDSDIWLFGGRTVYKNFFAQNK 921
            .:|.::.||||||||||||.||||||||||.|:.||.|.|||||||||||||.|.||:|||.:||
Human  1220 GQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNK 1284

  Fly   922 HVMEFRAEQIEQTFNCNRGKLIQLACLVGSDYTTGIHGIGAVTALEILASFSGQDANGPGICNQS 986
            .|..::..........:|.|||.||.|:|||||.||..:|.|||:|||..|.|..
Human  1285 FVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHG---------- 1339

  Fly   987 VLQTLIKFRDWW-QAHKCSNLPPGSSARLALRKKLKNIELHEGFPSGAVVEAYLAPTIDDNRDAF 1050
             |:.|:||.:|| :|.|...:.| :.....::|||:.::|..|||:.||.||||.|.:||::.:|
Human  1340 -LEPLLKFSEWWHEAQKNPKIRP-NPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSF 1402

  Fly  1051 SWGTPDVESIREFTRKSFGWTTSKTDDILMPVMKKINEKKIQGSIRNYFTAKSALRVQQPHVSKR 1115
            .||.||::.||||.::.|||..:|||:.|.||:|:::.::.|..|.::|    .|..|:...:||
Human  1403 LWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFF----RLAQQEKEDAKR 1463

  Fly  1116 VQLAIDKMSGKIDETPEKPKKVTRTRRAKAAPPTDDDLAIADVATKAARPKRGKRKAAPESVVLD 1180
            ::  ..:::..:.....|.|:...:.....:...:.:..:.|.| |....|||......||..|.
Human  1464 IK--SQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFELLDKA-KGKTQKRGITNTLEESSSLK 1525

  Fly  1181 GELPSTSQ 1188
            .:..|.|:
Human  1526 RKRLSDSK 1533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus201	NP_001027230.1	rad2	1..1122	CDD:273166	328/1175 (28%)
		PIN_XPG	1..>121	CDD:189038	40/90 (44%)
		PIN_XPG	<814..1084	CDD:189038	126/272 (46%)
		H3TH_XPG	940..1045	CDD:188624	45/105 (43%)
BIVM-ERCC5	NP_001191354.2	rad2	484..1483	CDD:273166	330/1190 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094524at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101242
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910