DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mus201 and exo1

DIOPT Version :9

Sequence 1:	NP_001027230.1	Gene:	mus201 / 3772069	FlyBaseID:	FBgn0002887	Length:	1236	Species:	Drosophila melanogaster
Sequence 2:	XP_002932663.3	Gene:	exo1 / 100487930	XenbaseID:	XB-GENE-982078	Length:	736	Species:	Xenopus tropicalis

Alignment Length:	446	Identity:	96/446 - (21%)
Similarity:	164/446 - (36%)	Gaps:	105/446 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   818 LKSQKTSEEL--QELATNLAQERKELEIERNRQDR----MGMSISQRMSIDCQELLRLFGIPYIV 876
            |.|:|..|:.  ::..|||.:.::.|...:..:.|    ..::|:..|:.|..:..|..||..||
Frog    82 LPSKKDVEKARREKRQTNLQKGKQLLREGKLAEARECFARSVNITSSMAHDVIKAARAEGIDCIV 146

  Fly   877 APMEAEAQCAFLNATDLTHGTITDDSDIWLFGGRTVYKNF--FAQNKHVMEFR---AEQIEQTFN 936
            ||.||::|.|:||..:.....||:|||:..||.:.|....  |.....:.:.|   ...:...|
Frog   147 APFEADSQLAYLNKNEFAEAIITEDSDLLAFGCKKVILKMDKFGNGLEIDQARFGMCRSLGDVF- 210

  Fly   937 CNRGKLIQLACLVGSDYTTGIHGIGAVTALEILASFSGQDANGPGICNQSVLQTLIKFRDWWQAH 1001
             ...|...:..|.|.||...|||||...|.::|     :.||.|.|      .|:||
Frog   211 -TEEKFRYMCILSGCDYLPSIHGIGLAKACKLL-----KIANNPDI------TTVIK-------- 255

  Fly  1002 KCSNLPPGSSARLALRKKLK-NIELHEGFPSGAV--------------VEAYLAPT----IDDNR 1047
                         .:.:.|| ||.:.:|:..|.:              ||..|.|.    .|.|.
Frog   256 -------------KIGQYLKTNITVPDGYIEGFLRANNTFLYQLVFDPVERKLIPLNPYGDDVNP 307

  Fly  1048 DAFSWGTPDVESIREFTRKSFGWTTSKTDDILMPV---------MKKI---NEKKIQGSIRNYFT 1100
            :..|:..|::                 .|.:.:.:         ||:|   |....|.|.|:...
Frog   308 EELSYAGPNM-----------------GDSVALQIALGNMDINTMKQIDDYNPDNPQLSHRSQSW 355

  Fly  1101 AKSALRVQQPHVSKRVQLAIDKMSGKIDETPEKPKKVTRTRRAKAAPPTDDDLAIADVAT----- 1160
            ....|..:..|.:.......:....|.:|.......:..:::.....|.:|.::..|:.:
Frog   356 DSKQLNRKGAHTNSIWHTKSEPCKNKNEEKHSPRGLILSSKKQTVKRPYEDGVSDTDLLSQYSFS 420

  Fly  1161 --KAARPKRGK--RKAAPESVVLDGELPSTSQSIPKPEKCPRIPSSVEVIPQREKD 1212
              |.|||.|..  .:....:.:|.   |....:..:|:..|:..::.....||:|:
Frog   421 KNKKARPDRDSPVHQVPASTTILQ---PLDGANTKEPKHQPKTRNAFATFLQRQKE 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mus201	NP_001027230.1	rad2	1..1122	CDD:273166	79/345 (23%)
		PIN_XPG	1..>121	CDD:189038
		PIN_XPG	<814..1084	CDD:189038	70/304 (23%)
		H3TH_XPG	940..1045	CDD:188624	29/123 (24%)
exo1	XP_002932663.3	PIN_EXO1	1..201	CDD:350207	35/118 (30%)
exo1	XP_002932663.3	H3TH_EXO1	213..289	CDD:188628	25/107 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910