Protein Alignment mus201 and gen1

DIOPT Version :10

• Sequence 1: NP_001027230.1
• Gene: mus201 / 3772069
• FlyBaseID: FBgn0002887
• Length: 1236
• Species: Drosophila melanogaster
• Sequence 2: NP_001361766.1
• Gene: gen1 / 100145302
• XenbaseID: XB-GENE-940145
• Length: 927
• Species: Xenopus tropicalis
• Alignment Length: 529
• Identity: 117/529 - (22%)
• Similarity: 196/529 - (37%)
• Gaps: 176/529 - (33%)

  Fly   850 RMGMSISQRMSIDCQELLRLFGIPYIVAPMEAEAQCAFLNATDLTHGTITDDSDIWLFGGRTVYK 914
            :.|.|..:.:..:|..:|...|||::.|..||||.||:|||.....|.||:|.|::|:|.:|||:
 Frog   104 KAGRSYFKSVLKECLLMLECLGIPWVQAAGEAEAMCAYLNAHGYVDGCITNDGDVFLYGAQTVYR 168

  Fly   915 NFF--AQNKHVMEFRAEQIEQTFNCNRGKLIQLACLVGSDY-TTGIHGIGAVTALEILASFSGQD 976
            ||.  .::.||..:...:|:.....:|.:|:.||.|:|.|| ..|:.|:..|.||:::...:|
 Frog   169 NFTMNVKDPHVDCYEVSKIKAQLGLDREELVGLAILLGCDYLPKGVPGVRKVQALKLIEMLNG-- 231

  Fly   977 ANGPGICNQSVLQTLIKFRDW--------WQAHK----CS-NLPPGS-------------SARLA 1015
                    :|:||   :|..|        .:|.|    || ...|||             |.|..
 Frog   232 --------ESLLQ---RFYQWEKDCNERGTKAPKKKPHCSVCCHPGSAKDHERNGCKMCGSDRFC 285

  Fly  1016 ----------------LRKKLKN-IELH--------EGFPSGAVVEAYLAPTIDDNR--DAFSWG 1053
                            .|:|.:| :|.:        ||||...|::.:|   |:.|:  ....||
 Frog   286 EPHDYDYRCPCDWHKEQREKQENSVEFNIKRKSLRCEGFPYRQVIDEFL---INKNKLVKVLKWG 347

  Fly  1054 TPDVESIREFTRKSFGWTTSKTDDILMPVMK--KINEKK--------------IQGSIRN----- 1097
            .|.::..:.||.:...|....:.:.|:.::.  .:||:|              ::..|||
 Frog   348 RPSLQCFQNFTAERMDWPRHYSCEKLLVLLTYYDMNERKAGRENGTQLQAVRIVKTRIRNGSPCF 412

  Fly  1098 ---------YFTA--------------KSALRVQQPHVSKRVQLAIDKMSGKIDETPEKPKKVTR 1139
                     |..|              :|..|...|||       :.....:..|..|...|..:
 Frog   413 EIEWVKPDSYVFADDHPAESPLVTIEEESLFRAAYPHV-------VTMFHKEKQEAEENKLKCKK 470

  Fly  1140 TR-RAKAAPPTDD------DLAIADVATKA----------------ARPKRGKR---------KA 1172
            :: ::|||...||      :|::..|:.|.                .:|.|...         ..
 Frog   471 SKPKSKAADDLDDVASLLSELSLKPVSEKQPPLELQEDGGDSDSVHEKPARDSNFLSLSSDADSG 535

  Fly  1173 APESVVLDGELPS------TSQSIPKPEKC---------------PRIPSSVEVIPQREKDLEQM 1216
            ....::||.:..|      |:.:.|....|               |.|.:.:..:.....|.:..
 Frog   536 VERGILLDTKTDSEFFTSPTADNEPSNPLCSSPAPSNTQHLTAASPNISAVISELQLSSIDWDST 600

  Fly  1217 RLNKAKAAE 1225
            ..:|:..||
 Frog   601 SFSKSPQAE 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mus201	NP_001027230.1	rad2	1..1122	CDD:273166	92/371 (25%)
gen1	NP_001361766.1	PIN_GEN1	2..206	CDD:350217	37/101 (37%)
		H3TH_StructSpec-5'-nucleases	195..336	CDD:473957	38/156 (24%)
		Chromo_2	396..456	CDD:465841	10/66 (15%)