DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18749 and P4H2

DIOPT Version :9

Sequence 1:	NP_001027154.1	Gene:	CG18749 / 3771984	FlyBaseID:	FBgn0042182	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_566279.1	Gene:	P4H2 / 819804	AraportID:	AT3G06300	Length:	299	Species:	Arabidopsis thaliana

Alignment Length:	247	Identity:	70/247 - (28%)
Similarity:	105/247 - (42%)	Gaps:	50/247 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 VLATTQNCTAVVQKPSKKLHCRYNTSTTPFTRIAPLKMEELGLDPYMVVFHDVIYDTEIDGMLNS 321
            :|...|:.|.::..||              :.|.|.|::::...|...|:...:.|.|.|.:::.
plant    15 LLVLLQSSTCLISSPS--------------SIINPSKVKQVSSKPRAFVYEGFLTDLECDHLISL 65

  Fly   322 SDFGLSESV-------SGLKSEVRTSKDSHIVDAKT-----LNERVTDMTGLSMEMSDPFSLINY 374
            :...|..|.       ....|:||||..:.|...|.     :.::::..|.|..|..:...::.|
plant    66 AKENLQRSAVADNDNGESQVSDVRTSSGTFISKGKDPIVSGIEDKLSTWTFLPKENGEDLQVLRY 130

  Fly   375 GLGGHFILHHD-FHEYTNTTRLKQGDRIATVLFYLREVDSGGATVFP------------------ 420
            ..|..:..|.| ||:..|..|  .|.||||||.||..|..||.||||
plant   131 EHGQKYDAHFDYFHDKVNIAR--GGHRIATVLLYLSNVTKGGETVFPDAQEFSRRSLSENKDDLS 193

  Fly   421 ---MLNITVMPKKGSAVFWYNLHNSGAVNSKTLHTACPVISGSKYVLTKWIN 469
               ...|.|.||||:|:.::||......:..:||..||||.|.|:..||||:
plant   194 DCAKKGIAVKPKKGNALLFFNLQQDAIPDPFSLHGGCPVIEGEKWSATKWIH 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..166	CDD:285528
CG18749	NP_001027154.1	P4Hc	314..468	CDD:214780	57/187 (30%)
P4H2	NP_566279.1	P4Hc	55..245	CDD:214780	59/191 (31%)
P4H2	NP_566279.1	ShKT	259..299	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920